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Computer-aided classification of optical images for diagnosis of osteoarthritis in the finger joints
Zhang J.1; Wang J.Z.2; Yuan Z.1; Sobel E.S.1; Jiang H.1
2011-11-07
Source PublicationJournal of X-Ray Science and Technology
ISSN08953996
Volume19Issue:4Pages:531-544
Abstract

This study presents a computer-aided classification method to distinguish osteoarthritis finger joints from healthy ones based on the functional images captured by x-ray guided diffuse optical tomography. Three imaging features, joint space width, optical absorption, and scattering coefficients, are employed to train a Least Squares Support Vector Machine (LS-SVM) classifier for osteoarthritis classification. The 10-fold validation results show that all osteoarthritis joints are clearly identified and all healthy joints are ruled out by the LS-SVM classifier. The best sensitivity, specificity, and overall accuracy of the classification by experienced technicians based on manual calculation of optical properties and visual examination of optical images are only 85%, 93%, and 90%, respectively. Therefore, our LS-SVM based computer-aided classification is a considerably improved method for osteoarthritis diagnosis. © 2011 - IOS Press and the authors. All rights reserve.

KeywordDiffuse Optical Tomography Finger Joints Least Squares Support Vector Machine Osteoarthritis Statistical Analysis X-rays
DOI10.3233/XST-2011-0312
URLView the original
Indexed BySCI
WOS Research AreaInstruments & Instrumentation ; Optics ; Physics
WOS SubjectInstruments & Instrumentation ; Optics ; Physics, Applied
WOS IDWOS:000296146500009
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Cited Times [WOS]:8   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Affiliation1.University of Florida
2.Clemson University
3.Southwest Jiaotong University
Recommended Citation
GB/T 7714
Zhang J.,Wang J.Z.,Yuan Z.,et al. Computer-aided classification of optical images for diagnosis of osteoarthritis in the finger joints[J]. Journal of X-Ray Science and Technology,2011,19(4):531-544.
APA Zhang J.,Wang J.Z.,Yuan Z.,Sobel E.S.,&Jiang H..(2011).Computer-aided classification of optical images for diagnosis of osteoarthritis in the finger joints.Journal of X-Ray Science and Technology,19(4),531-544.
MLA Zhang J.,et al."Computer-aided classification of optical images for diagnosis of osteoarthritis in the finger joints".Journal of X-Ray Science and Technology 19.4(2011):531-544.
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