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Photoacoustic tomography imaging of the adult zebrafish by using unfocused and focused high-frequency ultrasound transducers
Liu Y.; Li D.; Yuan Z.
2016
Source PublicationApplied Sciences (Switzerland)
ISSN20763417
Volume6Issue:12
Abstract

The zebrafish model provides an essential platform for the study of human diseases or disorders due to the possession of about 87% homologous genes with human. However, it is still very challenging to noninvasively visualize the structure and function of adult zebrafish based on available optical imaging techniques. In this study, photoacoustic tomography (PAT) was utilized for high-resolution imaging of adult zebrafish by using focused and unfocused high-frequency (10 MHz) ultrasound transducers. We examined and compared the imaging results from the two categories of transducers with in vivo experimental tests, in which we discovered that the unfocused transducer is able to identify the inner organs of adult zebrafish with higher contrast but limited regional resolution, whereas the findings from the focused transducer were with high resolution but limited regional contrast for the recovered inner organs.

KeywordContrast Photoacoustic Tomography (Pat) UnFocused And Focused Transducers Zebrafish
DOI10.3390/app6120392
URLView the original
Indexed BySCI
WOS Research AreaChemistry ; Materials Science ; Physics
WOS SubjectChemistry, Multidisciplinary ; Materials Science, Multidisciplinary ; Physics, Applied
WOS IDWOS:000389533400018
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Citation statistics
Cited Times [WOS]:11   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
AffiliationUniversidade de Macau
Recommended Citation
GB/T 7714
Liu Y.,Li D.,Yuan Z.. Photoacoustic tomography imaging of the adult zebrafish by using unfocused and focused high-frequency ultrasound transducers[J]. Applied Sciences (Switzerland),2016,6(12).
APA Liu Y.,Li D.,&Yuan Z..(2016).Photoacoustic tomography imaging of the adult zebrafish by using unfocused and focused high-frequency ultrasound transducers.Applied Sciences (Switzerland),6(12).
MLA Liu Y.,et al."Photoacoustic tomography imaging of the adult zebrafish by using unfocused and focused high-frequency ultrasound transducers".Applied Sciences (Switzerland) 6.12(2016).
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