Semiconducting polymer dot as a highly effective contrast agent for photoacoustic imaging
Yuan Z.; Zhang J.
Source PublicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
AbstractIn this study, we developed a novel PIID-DTBT based semiconducting polymer dots (Pdots) that have broad and strong optical absorption in the visible-light region (500 nm - 700 nm). Gold nanoparticles (GNPs) and gold nanorods (GNRs) that have been verified as an excellent photoacoustic contrast agent were compared with Pdots based on photoacoustic imaging method. Both ex vivo and in vivo experiment demonstrated Pdots have a better photoacoustic conversion efficiency at 532 nm than GNPs and similar photoacoustic performance with GNRs at 700 nm at the same mass concentration. Our work demonstrates the great potential of Pdots as a highly effective contrast agent for precise localization of lesions relative to the blood vessels based on photoacoustic tomography imaging.
KeywordPhotoacoustic Imaging Polymer Dots
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Document TypeConference paper
CollectionUniversity of Macau
AffiliationUniversidade de Macau
Recommended Citation
GB/T 7714
Yuan Z.,Zhang J.. Semiconducting polymer dot as a highly effective contrast agent for photoacoustic imaging[C],2018.
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