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Anti-cancer natural products isolated from chinese medicinal herbs
Tan W1,2; Lu JJ1,2,3; Huang MQ1,2,4; Li YB1,2; Chen MW1,2; Wu GS1,2; Gong J1,2; Zhong ZF1,2; Xu ZT1,2; Dang YY1,2; Guo JJ1,2; Chen XP1,2; Wang YT1,2
2011
Source PublicationChinese Medicine
ISSN1991-0150
Volume6Issue:1
Abstract

In recent years, a number of natural products isolated from Chinese herbs have been found to inhibit proliferation, induce apoptosis, suppress angiogenesis, retard metastasis and enhance chemotherapy, exhibiting anti-cancer potential both in vitro and in vivo. This article summarizes recent advances in in vitro and in vivo research on the anti-cancer effects and related mechanisms of some promising natural products. These natural products are also reviewed for their therapeutic potentials, including flavonoids (gambogic acid, curcumin, wogonin and silibinin), alkaloids (berberine), terpenes (artemisinin, β-elemene, oridonin, triptolide, and ursolic acid), quinones (shikonin and emodin) and saponins (ginsenoside Rg3), which are isolated from Chinese medicinal herbs. In particular, the discovery of the new use of artemisinin derivatives as excellent anti-cancer drugs is also reviewed.

DOIhttps://doi.org/10.1186/1749-8546-6-27
Indexed BySCI
Language英语
WOS Research AreaIntegrative & Complementary Medicine ; Pharmacology & Pharmacy
WOS SubjectIntegrative & Complementary Medicine ; Pharmacology & Pharmacy
WOS IDWOS:000208722100027
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Cited Times [WOS]:194   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Av. Padre Toma's Pereira S.J., Taipa, Macao SAR, China
2.Institute of Chinese Medical Sciences, University of Macau, Av. Padre Toma's Pereira S.J., Taipa, Macao SAR, China
3.College of Life Sciences, Zhejiang Chinese Medical University, 548 Binwen Rd., Binjiang Dist., Hangzhou 310053, Zhejiang, China
4.College of Pharmacy, Fujian University of Traditional Chinese Medicine, No.1 Huatuo Rd., Shangjie University Town, Fuzhou 350108, Fujian, China
First Author AffilicationUniversity of Macau;  Institute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Tan W,Lu JJ,Huang MQ,et al. Anti-cancer natural products isolated from chinese medicinal herbs[J]. Chinese Medicine,2011,6(1).
APA Tan W.,Lu JJ.,Huang MQ.,Li YB.,Chen MW.,...&Wang YT.(2011).Anti-cancer natural products isolated from chinese medicinal herbs.Chinese Medicine,6(1).
MLA Tan W,et al."Anti-cancer natural products isolated from chinese medicinal herbs".Chinese Medicine 6.1(2011).
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