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Two natural glucomannan polymers, from Konjac and Bletilla, as bioactive materials for pharmaceutical applications
Wang Y; Liu JJ; Li Q; Wang YT; Wang CM
2015-01
Source PublicationBiotechnology Letters
ISSN0141-5492
Volume37Issue:1Pages:1-8
Abstract

Next-generation biomaterials are expected to possess both desirable mechanical features and unique biological functions. Recently, two plant-derived glucomannans (GMs)-Konjac glucomannan (KGM) and the polysaccharide of Bletilla striata (BSP)-have emerged as new sources for development of biomaterials. They have been fabricated into drug delivery vehicles and wound healing dressings in varying shapes and sizes, and demonstrated strong gelling properties, high biocompatibility and remarkable convenience for processing and modification. Notably, they demonstrate bioactivities such as response to enzymes produced in special biological niches and/or affinity for carbohydrate receptors on specific cells. All these mechanical and biological advantages suggest these two GMs have great potential for future development and broader application in various biomedical and pharmaceutical fields.

KeywordBiomaterials Bletilla Striata Drug Delivery Konjac Glucomannan Polysaccharides Wound Healing
DOIhttp://dx.doi.org/10.1007/s10529-014-1647-6
Indexed BySCI
Language英语
WOS Research AreaBiotechnology & Applied Microbiology
WOS SubjectBiotechnology & Applied Microbiology
WOS IDWOS:000347028400001
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Cited Times [WOS]:34   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
AffiliationState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Avenida da Universidade, Macau, Taipa, SAR, China.
First Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Wang Y,Liu JJ,Li Q,et al. Two natural glucomannan polymers, from Konjac and Bletilla, as bioactive materials for pharmaceutical applications[J]. Biotechnology Letters,2015,37(1):1-8.
APA Wang Y,Liu JJ,Li Q,Wang YT,&Wang CM.(2015).Two natural glucomannan polymers, from Konjac and Bletilla, as bioactive materials for pharmaceutical applications.Biotechnology Letters,37(1),1-8.
MLA Wang Y,et al."Two natural glucomannan polymers, from Konjac and Bletilla, as bioactive materials for pharmaceutical applications".Biotechnology Letters 37.1(2015):1-8.
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