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A handheld 50pM-sensitivity micro-NMR CMOS platform with B-field stabilization for multi-type biological/chemical assays
Ka-Meng Lei1; Hadi Heidari2,3; Pui-In Mak1; Man-Kay Law1; Franco Maloberti2; Rui P. Martins1,4
2016-02-23
Conference Name63rd IEEE International Solid-State Circuits Conference, ISSCC 2016
Source PublicationDigest of Technical Papers - IEEE International Solid-State Circuits Conference
Volume59
Pages474-475
Conference Date31 Jan.-4 Feb. 2016
Conference PlaceSan Francisco, CA, United states
Author of SourceInstitute of Electrical and Electronics Engineers Inc.
Abstract

Point-of-use (PoU) biological/chemical assays are aimed to transform bulky laboratory instruments into easy-to-use lab-on-a-chip platforms, bringing down the cost, size, and sample-use by orders of magnitude [1,2]. Micro-Nuclear Magnetic Resonance (NMR) is a trail-blazing tool for target pinpointing, by utilizing functionalized magnetic nanoparticles (MNPs) as the probe [3]. Screening by micro-NMR is repeatable, versatile and low-cost as it is label- and washing-free for the samples, and immobilization-free for the electrodes. Herein, a high-sensitivity micro-NMR CMOS platform with magnetic (B)-field stabilization and thermal management is reported (Fig. 28.1.1). This handheld tool unifies multi-type assays (target detection, protein state analysis, and solvent-polymer dynamics), and is suitable for healthcare, food industry, and colloidal applications. © 2016 IEEE.

DOIhttp://doi.org/10.1109/ISSCC.2016.7418113
Indexed BySCI
Language英语
WOS Research AreaEngineering
WOS SubjectEngineering, Electrical & Electronic
WOS IDWOS:000382151400197
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Citation statistics
Cited Times [WOS]:7   [WOS Record]     [Related Records in WOS]
Document TypeConference paper
CollectionINSTITUTE OF MICROELECTRONICS
DEPARTMENT OF ELECTRICAL AND COMPUTER ENGINEERING
Affiliation1.University of Macau, China;
2.University of Pavia, Pavia, Italy;
3.University of Glasgow, Glasgow, United Kingdom;
4.Instituto Superior Tecnico, Lisbon, Portugal
First Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Ka-Meng Lei,Hadi Heidari,Pui-In Mak,et al. A handheld 50pM-sensitivity micro-NMR CMOS platform with B-field stabilization for multi-type biological/chemical assays[C]//Institute of Electrical and Electronics Engineers Inc.,2016:474-475.
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