UM
A G-triplex luminescent switch-on probe for the detection of mung bean nuclease activity
Ma D.-L.1; Lu L.1; Lin S.1; He B.1; Leung C.-H.2
2015-01-21
Source PublicationJournal of Materials Chemistry B
ISSN2050750X 20507518
Volume3Issue:3Pages:348-352
AbstractA cyclometallated Ir(III) complex was synthesised and evaluated for the ability to act as a luminescent G-triplex probe. The iridium(III) complex 1 [Ir(phq)(2,9-dmphen)]PF (where phq = 2-phenylquinoline; 2,9-dmphen = 2,9-dimethyl-1,10-phenanthroline) exhibited high luminescence for G-triplex DNA over dsDNA and ssDNA, and was employed to construct a label-free G-triplex-based assay for mung bean nuclease activity in aqueous solution. This method was highly sensitive and selective for MB nuclease activity over other DNA-modifying enzymes.
DOI10.1039/c4tb01569j
URLView the original
Language英語
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被引频次[WOS]:11   [WOS记录]     [WOS相关记录]
Document TypeJournal article
专题University of Macau
Affiliation1.Hong Kong Baptist University
2.University of Macau
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Ma D.-L.,Lu L.,Lin S.,et al. A G-triplex luminescent switch-on probe for the detection of mung bean nuclease activity[J]. Journal of Materials Chemistry B,2015,3(3):348-352.
APA Ma D.-L.,Lu L.,Lin S.,He B.,&Leung C.-H..(2015).A G-triplex luminescent switch-on probe for the detection of mung bean nuclease activity.Journal of Materials Chemistry B,3(3),348-352.
MLA Ma D.-L.,et al."A G-triplex luminescent switch-on probe for the detection of mung bean nuclease activity".Journal of Materials Chemistry B 3.3(2015):348-352.
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