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Prevalence of major depressive disorder in children and adolescents in China: A systematic review and meta-analysis
Xu Dan-Dan1,2; Rao Wen-Wang1; Cao Xiao-Lan3; Wen Si-Ying3; Che Weng-Ian4; Chee, Ng H.5; Ungvari, Gabor S.6; Du Yasong7; Zhang Ling8; Xiang Yu-Tao1
2018-12
Source PublicationJOURNAL OF AFFECTIVE DISORDERS
ISSN0165-0327
Volume241Pages:592-598
Abstract

Background

Prevalence figures of major depressive disorder (MDD) in children and adolescents across various epidemiological studies have been inconclusive. This is a systematic review and meta-analysis of the pooled prevalence of MDD and its associated factors in children and adolescents in China.

Method

A systematic review and literature search were conducted covering PubMed, PsycINFO, EMBASE and Chinese databases (China National Knowledge Internet, WANFANG Data and SinoMed) to identify studies reporting the prevalence of MDD in children and adolescents in China. The pooled prevalence estimates and associated factors were examined using the Comprehensive Meta-Analysis program, Version 2.

Results

Fourteen studies involving 82,592 subjects were included in this meta-analysis. The pooled point prevalence of MDD in Chinese children and adolescents was 1.3% (95% CI: 0.8%–2.0%). Subgroup and meta-regression analyses revealed that diagnostic criteria, age, year of survey and study quality were significantly associated with the prevalence of MDD.

Conclusions

The point prevalence of MDD in children and adolescents in China is similar to worldwide figures. Further national epidemiological studies with the view of developing effective intervention strategies should be considered.

KeywordDepression Children Adolescents Prevalence Meta-analysis China
DOI10.1016/j.jad.2018.07.083
URLView the original
Indexed BySCI ; SSCI ; SSCI
Language英语
WOS Research AreaNeurosciences & Neurology ; Psychiatry
WOS SubjectClinical Neurology ; Psychiatry
WOS IDWOS:000443816800078
PublisherELSEVIER SCIENCE BV
The Source to ArticleWOS
Fulltext Access
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Cited Times [WOS]:7   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Corresponding AuthorZhang Ling; Xiang Yu-Tao
Affiliation1.Unit of Psychiatry, Faculty of Health Sciences, University of Macau, 3/F, Building E12, Avenida da Universidade, Taipa, Macao SAR, China
2.Department of Biology, Faculty of Sciences, Harbin University, Harbin, China
3.Shenzhen Key Laboratory for Psychological Healthcare & Shenzhen Institute of Mental Health, Shenzhen Kangning Hospital & Shenzhen Mental Health Center, Shenzhen, China
4.Department of Public Health Science, Karolinska Institute, Stockholm, Sweden
5.Department of Psychiatry, University of Melbourne, Melbourne, Victoria, Australia
6.University of Notre Dame Australia & Graylands Hospital, Perth, Australia
7.Division of Psychiatry, Medical School, University of Western Australia, Perth, Australia
8.Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, China
9.The National Clinical Research Center for Mental Disorders, China & Center of Depression, Beijing Institute for Brain Disorders & Mood Disorders Center, Beijing Anding Hospital, Capital Medical University, Beijing, China
First Author AffilicationFaculty of Health Sciences
Corresponding Author AffilicationFaculty of Health Sciences
Recommended Citation
GB/T 7714
Xu Dan-Dan,Rao Wen-Wang,Cao Xiao-Lan,et al. Prevalence of major depressive disorder in children and adolescents in China: A systematic review and meta-analysis[J]. JOURNAL OF AFFECTIVE DISORDERS,2018,241:592-598.
APA Xu Dan-Dan.,Rao Wen-Wang.,Cao Xiao-Lan.,Wen Si-Ying.,Che Weng-Ian.,...&Xiang Yu-Tao.(2018).Prevalence of major depressive disorder in children and adolescents in China: A systematic review and meta-analysis.JOURNAL OF AFFECTIVE DISORDERS,241,592-598.
MLA Xu Dan-Dan,et al."Prevalence of major depressive disorder in children and adolescents in China: A systematic review and meta-analysis".JOURNAL OF AFFECTIVE DISORDERS 241(2018):592-598.
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