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Iridium(III) complexes with 1,10-phenanthroline-based N^N ligands as highly selective luminescent G-quadruplex probes and application for switch-on ribonuclease H detection
Lu L.2; Wang W.1; Yang C.3; Kang T.-S.3; Leung C.-H.3; Ma D.-L.1
2016
Source PublicationJournal of Materials Chemistry B
ISSN2050750X 20507518
Volume4Issue:42Pages:6791-6796
AbstractA systematic study was performed to investigate the relationship between molecular structure and G-quadruplex sensing ability for a series of structurally related cyclometallated iridium(iii) complexes. The novel complex 7 was used to construct a label-free luminescent switch-on G-quadruplex-based assay for RNase H activity in buffered solution. The constructed detection platform was simple, low-cost and highly sensitive for RNase H, and functioned effectively in the presence of cellular debris.
DOI10.1039/c6tb02316a
URLView the original
Language英語
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被引频次[WOS]:19   [WOS记录]     [WOS相关记录]
Document TypeJournal article
专题University of Macau
Affiliation1.Hong Kong Baptist University
2.Qingdao Agricultural University
3.University of Macau
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Lu L.,Wang W.,Yang C.,et al. Iridium(III) complexes with 1,10-phenanthroline-based N^N ligands as highly selective luminescent G-quadruplex probes and application for switch-on ribonuclease H detection[J]. Journal of Materials Chemistry B,2016,4(42):6791-6796.
APA Lu L.,Wang W.,Yang C.,Kang T.-S.,Leung C.-H.,&Ma D.-L..(2016).Iridium(III) complexes with 1,10-phenanthroline-based N^N ligands as highly selective luminescent G-quadruplex probes and application for switch-on ribonuclease H detection.Journal of Materials Chemistry B,4(42),6791-6796.
MLA Lu L.,et al."Iridium(III) complexes with 1,10-phenanthroline-based N^N ligands as highly selective luminescent G-quadruplex probes and application for switch-on ribonuclease H detection".Journal of Materials Chemistry B 4.42(2016):6791-6796.
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