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Quality control of polysaccharides from medicinal plants and fungi
Guan J.; Li S.-P.
AbstractPolysaccharides isolated from medicinal plants and fungi exhibit multiple pharmacological activities, including anti-tumor, anti-oxidation, hypoglycemic activity and immune potentiation and so on. The biological activities of polysaccharides depend on their chemical characteristics. However, quality control of polysaccahrides is a challenge because of their complicate structure, macro-molecular mass, more characters showed relationship with the bioactivities and more potential symbols could be used as the evaluation indicators. In this review, qualitative assay including the tests of purity, molecular weight and its distribution, constituent monosaccharide composition and the ratio, the features of glycosidic linkages, as well as quantitative analysis of polysaccharides from medicinal plants and fungi were reviewed and discussed. Among the various means for quality control of polysaccharides, chromatographic and electromigratic methods including high performance liquid chromatography (HPLC) such as high performance anion exchange chromatography (HPAEC), size exclusion chromatography (SEC) and electrophoresis (e.g. capillary electrophoresis and gel electrophoresis) are powerful techniques. The perspective for quality control of polysaccharides has also been described. © 2009 Nova Science Publishers, Inc. All rights reserved.
KeywordMedicinal fungi Medicinal plants Polysaccharides Qualification Quality control Quantitation
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Document TypeBook
CollectionInstitute of Chinese Medical Sciences
AffiliationUniversity of Macau
First Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Guan J.,Li S.-P.. Quality control of polysaccharides from medicinal plants and fungi[M],2009.
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