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Oplopanphesides A-C, three new phenolic glycosides from the root barks of Oplopanax horridus
Huang W.-H.2; Zhang Q.-W.2; Meng L.-Z.2; Yuan C.-S.1; Wang C.-Z.1; Li S.-P.2
2011-05-01
Source PublicationChemical and Pharmaceutical Bulletin
ISSN00092363 13475223
Volume59Issue:5Pages:676-679
Abstract

Three new phenolic glycosides, named oplopanphesides A-C (1-3), have been isolated from the root barks of Oplopanax horridus. Their structures were elucidated by a combination of spectroscopic analyses, including 1D- and 2D-NMR techniques. These phenolic glycosides possess a novel feature in their sugar moieties that a 3-hydroxy-3-methylglutaryl moiety was connected with C-6 of the β-D-glucopyranosyl group. Those compounds showed no cytotoxic effects against human cancer cell lines (MDA-231 and MCF-7) by 3-(4,5-dimethylthiazol-2- yl)-2,5-diphenyltetrazolium bromide (MTT) method. © 2011 Pharmaceutical Society of Japan.

Keyword3-hydroxy-3- Methylglutaryl Oplopanax Horridus Oplopanpheside Phenolic Glycoside
DOI10.1248/cpb.59.676
URLView the original
Indexed BySCI
WOS Research AreaPharmacology & Pharmacy ; Chemistry
WOS SubjectChemistry, Medicinal ; Chemistry, Multidisciplinary ; Pharmacology & Pharmacy
WOS IDWOS:000290194400024
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Cited Times [WOS]:9   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.University of Chicago Pritzker School of Medicine
2.University of Macau
First Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Huang W.-H.,Zhang Q.-W.,Meng L.-Z.,et al. Oplopanphesides A-C, three new phenolic glycosides from the root barks of Oplopanax horridus[J]. Chemical and Pharmaceutical Bulletin,2011,59(5):676-679.
APA Huang W.-H.,Zhang Q.-W.,Meng L.-Z.,Yuan C.-S.,Wang C.-Z.,&Li S.-P..(2011).Oplopanphesides A-C, three new phenolic glycosides from the root barks of Oplopanax horridus.Chemical and Pharmaceutical Bulletin,59(5),676-679.
MLA Huang W.-H.,et al."Oplopanphesides A-C, three new phenolic glycosides from the root barks of Oplopanax horridus".Chemical and Pharmaceutical Bulletin 59.5(2011):676-679.
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