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Research and development of therapeutic mAbs: An analysis based on pipeline projects
Geng X.1; Kong X.1; Hu H.1; Chen J.2,3,4; Yang F.5; Liang H.1; Chen X.1; Hu Y.1
2015
Source PublicationHuman Vaccines and Immunotherapeutics
ISSN2164554X 21645515
Volume11Issue:12Pages:2769-2776
Abstract

As the subject of active research and development (R&D) in recent decades, monoclonal antibodies have emerged among the major classes of therapeutic agents for treatment of many human diseases, especially cancers, infections, and immunological disorders. This article surveys the landscape of R&D projects of therapeutic monoclonal antibodies (mAbs), which are mostly used for disease immunotherapy, from a number of perspectives, including therapeutic indications, development phases, participants, and citation of related patents. The results of this research can be used as a reference resource for pharmaceutical researchers, investors, and policymakers in the field of therapeutic mAbs

KeywordDevelopment Trends Monoclonal Antibody Patent Citation Network Pipeline Projects r&d Therapeutic Application
DOI10.1080/21645515.2015.1074362
URLView the original
Indexed BySCI
WOS Research AreaBiotechnology & Applied Microbiology ; Immunology
WOS SubjectBiotechnology & Applied Microbiology ; Immunology
WOS IDWOS:000367066700015
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Cited Times [WOS]:18   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Macau, Peoples R China
2.Chongqing Univ, Coll Med Bioengn, Chongqing 630044, Peoples R China
3.Chongqing Univ, Fac Life Sci, Chongqing 630044, Peoples R China
4.Zunyi Med Coll, Dept Biochem & Mol Biol, Zunyi, Peoples R China
5.Chongqing Univ, Sch Chem & Chem Engn, Dept Pharmaceut, Chongqing 630044, Peoples R China
First Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Geng X.,Kong X.,Hu H.,et al. Research and development of therapeutic mAbs: An analysis based on pipeline projects[J]. Human Vaccines and Immunotherapeutics,2015,11(12):2769-2776.
APA Geng X..,Kong X..,Hu H..,Chen J..,Yang F..,...&Hu Y..(2015).Research and development of therapeutic mAbs: An analysis based on pipeline projects.Human Vaccines and Immunotherapeutics,11(12),2769-2776.
MLA Geng X.,et al."Research and development of therapeutic mAbs: An analysis based on pipeline projects".Human Vaccines and Immunotherapeutics 11.12(2015):2769-2776.
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