UM
Chromosomal mapping of a skeletal muscle specific LIM-only protein FHL3 to the distal end of the short arm of human chromosome 1
Lee S.M.Y.; Tsui S.K.W.; Chan K.K.; Kotaka M.; Li H.Y.; Chim S.S.C.; Waye M.M.Y.; Fung K.P.; Lee C.Y.
1998-12-01
Source PublicationSomatic Cell and Molecular Genetics
ISSN07407750
Volume24Issue:3Pages:197-202
AbstractFour-and-a-half LIM domain proteins (FHL) possess four tandem repeats of LIM domain and an extra zinc finger. FHL family LIM proteins are unique when compared with other LIM-only proteins because they possess an odd number of zinc fingers. In this study, the tissue distribution and chromosomal mapping of skeletal muscle LIM protein FHL3 were reported. When the FHL3 cDNA probe was used to hybridize with poly-(A) RNA of various human tissues, a very strong signal was detected in skeletal muscle, and virtually no signal could be detected in heart, brain, placenta, lung, liver, kidney and pancreas. Using radiation hybrid technique, FHL3 gene was mapped to the distal end of the short arm of chromosome 1 (123.26 cR from the top of the Chr1 linkage group) and this region (near 1p34) is related to several human malignancies.
DOI10.1023/B:SCAM.0000007122.03392.4b
URLView the original
Language英語
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Cited Times [WOS]:14   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
AffiliationChinese University of Hong Kong
Recommended Citation
GB/T 7714
Lee S.M.Y.,Tsui S.K.W.,Chan K.K.,et al. Chromosomal mapping of a skeletal muscle specific LIM-only protein FHL3 to the distal end of the short arm of human chromosome 1[J]. Somatic Cell and Molecular Genetics,1998,24(3):197-202.
APA Lee S.M.Y..,Tsui S.K.W..,Chan K.K..,Kotaka M..,Li H.Y..,...&Lee C.Y..(1998).Chromosomal mapping of a skeletal muscle specific LIM-only protein FHL3 to the distal end of the short arm of human chromosome 1.Somatic Cell and Molecular Genetics,24(3),197-202.
MLA Lee S.M.Y.,et al."Chromosomal mapping of a skeletal muscle specific LIM-only protein FHL3 to the distal end of the short arm of human chromosome 1".Somatic Cell and Molecular Genetics 24.3(1998):197-202.
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