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An eco-friendly: In situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine
Li S.1; Jiang N.1; Zhao W.1; Ding Y.-F.1; Zheng Y.1; Wang L.-H.2; Zheng J.1; Wang R.1
2017
Source PublicationChemical Communications
ISSN1364548X 13597345
Volume53Issue:43Pages:5870-5873
Abstract

We report an unprecedented, eco-friendly, in situ activatable model antibiotic, phenylalanyl-polyethylenimine (PhePEI), to potentially diminish antibiotic pollution of the environment and associated antibiotic resistance. The inactive PhePEI can be reversibly activated upon supramolecular crosslinking by cucurbit[8]uril, conferring potent antibacterial activity.

DOI10.1039/c7cc02466e
URLView the original
Indexed BySCI
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000402296200019
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Cited Times [WOS]:26   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Institute of Chinese Medical Sciences
Affiliation1.University of Macau
2.Nanjing University of Post and TeleCommunications
First Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Li S.,Jiang N.,Zhao W.,et al. An eco-friendly: In situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine[J]. Chemical Communications,2017,53(43):5870-5873.
APA Li S..,Jiang N..,Zhao W..,Ding Y.-F..,Zheng Y..,...&Wang R..(2017).An eco-friendly: In situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine.Chemical Communications,53(43),5870-5873.
MLA Li S.,et al."An eco-friendly: In situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine".Chemical Communications 53.43(2017):5870-5873.
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