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Corni Fructus: a review of chemical constituents and pharmacological activities
Dong, Yu; Feng, Zhe-Ling; Chen, Hu-Biao; Wang, Fu-Sheng; Lu, Jia-Hong
2018-06-25
Source PublicationCHINESE MEDICINE
ISSN1749-8546
Volume13
AbstractCornus officinalis Sieb. et Zucc. is part of the genus Cornus of the family Cornaceae. Ripening and dry fruits (Corni Fructus) are recognized as an essential herb medicine in the traditional Chinese medicine (TCM) and have been widely used for over 2000 years. This review provides a comprehensive summary of Corni Fructus (CF), including the botany, phytochemistry, traditional use, and current pharmacological activities. According to the basic theory of TCM, CF usually participates in various Chinese medicinal formulae to exert the essential roles in replenishing liver and kidney, arresting seminal emission and sweat. Based on modern pharmacological studies, about 90 compounds have been isolated and identified from CF. In vivo and in vitro experimental studies indicate that CF exhibits extensive pharmacological activities including hypoglycemic, antioxidant, anti-inflammatory, anticancer, neuroprotective, hepatoprotective, and nephroprotective activities. However, only about 18% of chemical constituents in CF were tested. It means the potential pharmacological activities and clinical values of CF need to be further investigated.
KeywordCornus officinalis Sieb. et Zucc. Corni Fructus Shan Zhu Yu Phytochemistry Pharmacological activity
DOI10.1186/s13020-018-0191-z
URLView the original
Indexed BySCI
Language英语
WOS Research AreaIntegrative & Complementary Medicine ; Pharmacology & Pharmacy
WOS SubjectIntegrative & Complementary Medicine ; Pharmacology & Pharmacy
WOS IDWOS:000436811200001
PublisherBMC
The Source to ArticleWOS
Fulltext Access
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Cited Times [WOS]:1   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Recommended Citation
GB/T 7714
Dong, Yu,Feng, Zhe-Ling,Chen, Hu-Biao,et al. Corni Fructus: a review of chemical constituents and pharmacological activities[J]. CHINESE MEDICINE,2018,13.
APA Dong, Yu,Feng, Zhe-Ling,Chen, Hu-Biao,Wang, Fu-Sheng,&Lu, Jia-Hong.(2018).Corni Fructus: a review of chemical constituents and pharmacological activities.CHINESE MEDICINE,13.
MLA Dong, Yu,et al."Corni Fructus: a review of chemical constituents and pharmacological activities".CHINESE MEDICINE 13(2018).
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