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A Novel strategy for quantitative analysis of major ginsenosides in panacis japonici rhizoma with a standardized reference fraction
Meng F.-C.2; Wu Q.-S.2; Wang R.2; Li S.-P.2; Lin L.-G.2; Chen P.1; Zhang Q.-W.2
2017-12-01
Source PublicationMolecules
ISSN14203049
Volume22Issue:12
Abstract

Panacis Japonici Rhizoma (Zhu-Jie-Shen in Chinese), the root of P. japonicus C.A. Mey., is commonly used in traditional Chinese Medicine. Saponins are the major bioactive compounds in this herb. The similarity of polarity and structure of the natural products in herb caused the difficulty of purification and resulted in the shortage and high cost of the reference compounds, which has greatly hindered efforts toward quantification in quality control. A novel strategy using a standardized reference fraction for qualification of the major saponins in Panacis Japonici Rhizoma was proposed to easily and effectively control the quality of PJR. The strategy is feasible and reliable, and the methodology of the developed approach is also validated. The standardized reference fraction was used for quantification, which might solve the shortage of the pure reference compounds in the quality control of herbal medicines.

KeywordChikusetsusaponin Ginsenoside Hplc Panacis Japonici Rhizoma PA.A. JA.oniC.s C. A. Mey Pseudoginsenoside Quality Control Quantification Standardized Reference Fraction Triterpenoid Saponin
DOI10.3390/molecules22122067
URLView the original
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS SubjectBiochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS IDWOS:000419242400037
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Cited Times [WOS]:4   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.Wuhan Polytechnic University
2.University of Macau
First Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Meng F.-C.,Wu Q.-S.,Wang R.,et al. A Novel strategy for quantitative analysis of major ginsenosides in panacis japonici rhizoma with a standardized reference fraction[J]. Molecules,2017,22(12).
APA Meng F.-C..,Wu Q.-S..,Wang R..,Li S.-P..,Lin L.-G..,...&Zhang Q.-W..(2017).A Novel strategy for quantitative analysis of major ginsenosides in panacis japonici rhizoma with a standardized reference fraction.Molecules,22(12).
MLA Meng F.-C.,et al."A Novel strategy for quantitative analysis of major ginsenosides in panacis japonici rhizoma with a standardized reference fraction".Molecules 22.12(2017).
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