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Phytochemical Investigation of Corydalis yanhusuo
Alternative Title延胡索的化学成分研究
SHI Jun-minm1; HAN Wei-li2; YE Wen-cai3; CHAN Shek-kiu4; WANG Yi-tao5; ZHANG Qing-wen6
2011
Source PublicationNatural Product R & D
ISSN1001-6880
Volume23Issue:4Pages:647-651
Abstract

Seventeen compounds have been isolated from Corydalis yanhusuo W.T.Wang.Their structures were deduced on the basis of their physicochenical properties and spectroscopic data.These compounds,including eleven alkaloids,two anthraquinones,a triterpenoid and three steroids,were identified as dihydrochelerythrine (1),dehydrocorydaline (2),tetrahydrocolumbamine (3),isocorybulbine (4),corydaline (5),tetrahydrocoptisine (6),jatrorrhizine (7),coptisine (8),emodin (9),physcion (10),3beta-hydroxy-olean-11,13 (18)-dien-28-oic acid (11),berberine (12),palmatine (13),tetrahydropalmatine (14),stigmasterol (15),beta-sitosterol (16),and daucosterol (17).Compounds 9-11 were isolated from genus Corydalis for the first time,and 1 was firstly isolated from this species.

Other Abstract

摘要:采用现代分离技术和方法,从延胡索根茎中分离得到17个化合物,通过波谱分析鉴定其结构。包括11个生物碱类化合物,二氢白屈菜红碱(1)、去氢紫堇碱(2)、四氢非洲防己胺(3)、异紫堇球碱(4)、紫堇碱(5)、四氢黄连碱(6)、药根碱(7)、黄连碱(8)、小檗碱(12)、巴马汀(13)和延胡索乙素(14);2个蒽醌类化合物,大黄素 (9)和大黄素甲醚(10);1个三萜类化合物,即3beta-羟基-齐墩果烷-11,13(18)-二烯-28-酸(11)和3个甾醇类化合物,豆甾醇(15)、beta-谷甾醇(16)和胡萝卜苷(17)。其中,化合物911首次从该属植物中分离得到,1首次从该种中分离得到。

KeywordCorydalis Yanhusuo Isoquinoline Alkaloid Anthraquinone Triterpenoid
DOI1001-6880(2011)23:4<647:PIOCY>2.0.TX;2-C
Language英语
WOS Research AreaGeneral & Internal Medicine
CSCD IDCSCD:4278897
The Source to ArticleWOS
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Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.Institute of Chinese Medical Sciences,University of Macau, Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Macau.
2.Institute of Traditional Chinese Medicine and Natural Products,Jinan University, Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research.
3.Institute of Traditional Chinese Medicine and Natural Products,Jinan University, Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research.
4.Faculty of Science and Technology,University of Macau, Macau.
5.Institute of Chinese Medical Sciences,University of Macau, Macau.
6.Institute of Chinese Medical Sciences,University of Macau, Macau.
First Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
SHI Jun-minm,HAN Wei-li,YE Wen-cai,et al. Phytochemical Investigation of Corydalis yanhusuo[J]. Natural Product R & D,2011,23(4):647-651.
APA SHI Jun-minm,HAN Wei-li,YE Wen-cai,CHAN Shek-kiu,WANG Yi-tao,&ZHANG Qing-wen.(2011).Phytochemical Investigation of Corydalis yanhusuo.Natural Product R & D,23(4),647-651.
MLA SHI Jun-minm,et al."Phytochemical Investigation of Corydalis yanhusuo".Natural Product R & D 23.4(2011):647-651.
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