UM  > 中華醫藥研究院
Asymmetry between the superior and inferior endplates is a risk factor for lumbar disc degeneration
Wang, Yitao1; Wang, Hongli1; Lv, Feizhou1,2; Ma, Xiaosheng1; Xia, Xinlei1; Jiang, Jianyuan1
2018-09
Source PublicationJOURNAL OF ORTHOPAEDIC RESEARCH
ISSN0736-0266
Volume36Issue:9Pages:2469-2475
AbstractEndplate pathology plays an important role in the development of lumbar disc degeneration. Previous research paid little attention to differences between the superior and inferior endplates as a possible risk factor for disc degeneration. The purpose of this study was to test the hypothesis that asymmetry between the superior and inferior endplates is a risk factor for the development of lumbar disc degeneration. A total of 134 patients with lumbar disc herniation (LDH) and 100 healthy adults (Controls) underwent magnetic resonance imaging scans. Each disc was categorized as non-degenerated (Pfirrmann grades I-II) or degenerated (Pfirrmann grades III-V) and get the following three groups: Degenerated LDH discs (n=145), Non-degenerated LDH discs (n=525) and Non-degenerated Control discs (n=500). On mid-sagittal image, the lumbar endplate morphology could be categorized into three types: Flat, concave, and irregular. Superior and inferior endplates of a given disc were symmetric if both were of the same type, and asymmetric if they were of different types. The proportion of asymmetric endplates at L4-5 was higher in the Degenerated LDH discs group (47%) than in the Non-degenerated LDH discs group (21%) or Non-degenerated Control discs group (7%) (p<0.05). At L5-S1 the proportions were 73%, 55%, and 38% (p<0.05). Asymmetry of superior and inferior endplates in the mid-sagittal plane is a risk factor for lumbar disc degeneration. (c) 2018 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:2469-2475, 2018.
Keywordendplate endplate morphology lumbar disc degeneration lumbar disc herniation magnetic resonance imaging
DOI10.1002/jor.23906
URLView the original
Indexed BySCI
Language英语
WOS Research AreaOrthopedics
WOS SubjectOrthopedics
WOS IDWOS:000443808900017
PublisherWILEY
The Source to ArticleWOS
Fulltext Access
Citation statistics
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.Fudan Univ, Huashan Hosp, Dept Orthoped, 12 Wulumuqi Rd M, Shanghai, Peoples R China;
2.Fudan Univ, Peoples Hosp Shanghai 5, Shanghai, Peoples R China
Recommended Citation
GB/T 7714
Wang, Yitao,Wang, Hongli,Lv, Feizhou,et al. Asymmetry between the superior and inferior endplates is a risk factor for lumbar disc degeneration[J]. JOURNAL OF ORTHOPAEDIC RESEARCH,2018,36(9):2469-2475.
APA Wang, Yitao,Wang, Hongli,Lv, Feizhou,Ma, Xiaosheng,Xia, Xinlei,&Jiang, Jianyuan.(2018).Asymmetry between the superior and inferior endplates is a risk factor for lumbar disc degeneration.JOURNAL OF ORTHOPAEDIC RESEARCH,36(9),2469-2475.
MLA Wang, Yitao,et al."Asymmetry between the superior and inferior endplates is a risk factor for lumbar disc degeneration".JOURNAL OF ORTHOPAEDIC RESEARCH 36.9(2018):2469-2475.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Wang, Yitao]'s Articles
[Wang, Hongli]'s Articles
[Lv, Feizhou]'s Articles
Baidu academic
Similar articles in Baidu academic
[Wang, Yitao]'s Articles
[Wang, Hongli]'s Articles
[Lv, Feizhou]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Wang, Yitao]'s Articles
[Wang, Hongli]'s Articles
[Lv, Feizhou]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.