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Applications of nanoparticles in herbal medicine: Zedoary turmeric oil and its active compound β-elemene
Chen M.; Wang S.; Tan M.; Wang Y.
2011
Source PublicationAmerican Journal of Chinese Medicine
Volume39Issue:6Pages:1093
AbstractZedoary turmeric oil and its main active ingredient β-elemene are novel plant-derived anticancer agents with long-term clinical application history and low toxicity, which have been approved by the Chinese SFDA to treat different tumors including cancers of the brain, ovary, prostate, breast, lungs, liver, colon, and other tissues. Unfortunately, their hydrophobic properties, poor stabilities and low bioavailabilities seriously hamper their applications in clinic. Therefore, more attention should be paid to develop novel drug delivery systems for zedoary turmeric oil and β-elemene to enhance their overall quality. Recently, increased research has been carried out on a nanoparticle drug delivery system of zedoary turmeric oil and β-elemene to solve their poor aqueous solubilities and low bioavailabilities in vivo with much remarkable achievements springing up in the last decade. This review presents the novel nanoparticle formulations of zedoary turmeric oil and β-elemene and introduces the possible future prospects of their further study. © 2011 World Scientific Publishing Company & Institute for Advanced Research in Asian Science and Medicine.
Keywordβ-Elemene Nanoparticle Drug Delivery of Systems Research Perspectives Review Zedoary Turmeric Oil
DOI10.1142/S0192415X11009421
URLView the original
Language英语
The Source to ArticleScopus
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被引频次[WOS]:14   [WOS记录]     [WOS相关记录]
Document TypeJournal article
专题Institute of Chinese Medical Sciences
AffiliationState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Av. Padre Tomas Pereira S.J., Taipa, Macau
First Author AffilicationInstitute of Chinese Medical Sciences
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Chen M.,Wang S.,Tan M.,et al. Applications of nanoparticles in herbal medicine: Zedoary turmeric oil and its active compound β-elemene[J]. American Journal of Chinese Medicine,2011,39(6):1093.
APA Chen M.,Wang S.,Tan M.,&Wang Y..(2011).Applications of nanoparticles in herbal medicine: Zedoary turmeric oil and its active compound β-elemene.American Journal of Chinese Medicine,39(6),1093.
MLA Chen M.,et al."Applications of nanoparticles in herbal medicine: Zedoary turmeric oil and its active compound β-elemene".American Journal of Chinese Medicine 39.6(2011):1093.
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