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Stability of dietary polyphenols: It's never too late to mend?
Xiao, Jianbo
2018-09
Conference Name3rd International Symposium on Phytochemicals in Medicine and Food (ISPMF)
Source PublicationFOOD AND CHEMICAL TOXICOLOGY
Volume119
Pages3-5
Conference DateAUG 25-30, 2018
Conference PlaceKunming, PEOPLES R CHINA
Publication PlaceTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
PublisherPERGAMON-ELSEVIER SCIENCE LTD
Abstract

We have comprehensively investigated the structure-stability relationship of natural polyphenols in DMEM medium without cells. Polyphenols with catechol or pyrogallol structure were evidently instable in DMEM medium without cells. Herein, we further investigate stability of polyphenols when incubated with cancer cells and its related mechanism. After incubated with SK-28 cells and A549 cells at 37 degrees C in 5% CO2 for 72 h, the new products of quercetin and 5,7,3',4'-tetrahydroxyflavone were found to quite different from different cells. It is time to investigate what really happened for polyphenols and the new products of polyphenols in cancer cells, as well as the related mechanism. It is very important to further check the bioactivity of these new products, which will avoid erroneous conclusions for what's the really bioactive compounds.

KeywordStability Dietary Polyphenols Cells Quercetin 5,7,3 ',4 '-tetrahydroxyflavone New Products
DOI10.1016/j.fct.2018.03.051
URLView the original
Indexed BySCI ; CPCI
Language英语
WOS Research AreaFood Science & Technology ; Toxicology
WOS SubjectFood Science & Technology ; Toxicology
WOS IDWOS:000443664200002
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Cited Times [WOS]:19   [WOS Record]     [Related Records in WOS]
Document TypeConference paper
CollectionInstitute of Chinese Medical Sciences
AffiliationUniv Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Taipa, Macau, Peoples R China
First Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Xiao, Jianbo. Stability of dietary polyphenols: It's never too late to mend?[C]. THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND:PERGAMON-ELSEVIER SCIENCE LTD,2018:3-5.
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