UM  > 健康科學學院
Construction of Thermo-Responsive Elastin-Like Polypeptides (ELPs)-Aggregation-Induced-Emission (AIE) Conjugates for Temperature Sensing
Chen, Zhe1,2; Ding, Zhaoyang1; Zhang, Guangya3; Tian, Leilei2; Zhang, Xuanjun1
2018-07
Source PublicationMOLECULES
ISSN1420-3049
Volume23Issue:7
Abstract

In this work, an aggregation-induced emission (AIE) molecule (tetraphenylethene derivative, TPE-COOH) was conjugated to elastin-like polypeptides (ELPs40) via an amide bond to form ELPs40-TPE. The successful synthesis of ELPs40-TPE was confirmed by Circular Dichroism spectroscopy, gel electrophoresis, UV-vis absorption, and fluorescence emission spectroscopy. ELPs40-TPE possessed both amphiphilicity and the features of an AIE, and the fluorescence intensity was dependent on the local temperature. The Hela cells imaging indicated that ELPs40-TPE has great potential for bio-imaging applications because of its advantages of high fluorescence intensity, good water-solubility, and remarkable biocompatibility.

KeywordElastin-like Polypeptides (Elps) Aggregation-induced-emission (Aie) Thermo-responsive Temperature Sensing
DOI10.3390/molecules23071725
URLView the original
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS SubjectBiochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS IDWOS:000445301800228
PublisherMDPI
The Source to ArticleWOS
Fulltext Access
Citation statistics
Cited Times [WOS]:1   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Affiliation1.Univ Macau, Fac Hlth Sci, Taipa 999078, Macao, Peoples R China
2.Southern Univ Sci & Technol, Dept Mat Sci & Engn, Shenzhen 518055, Peoples R China
3.Huaqiao Univ, Dept Biotechnol & Bioengn, Xiamen 361021, Peoples R China
First Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Chen, Zhe,Ding, Zhaoyang,Zhang, Guangya,et al. Construction of Thermo-Responsive Elastin-Like Polypeptides (ELPs)-Aggregation-Induced-Emission (AIE) Conjugates for Temperature Sensing[J]. MOLECULES,2018,23(7).
APA Chen, Zhe,Ding, Zhaoyang,Zhang, Guangya,Tian, Leilei,&Zhang, Xuanjun.(2018).Construction of Thermo-Responsive Elastin-Like Polypeptides (ELPs)-Aggregation-Induced-Emission (AIE) Conjugates for Temperature Sensing.MOLECULES,23(7).
MLA Chen, Zhe,et al."Construction of Thermo-Responsive Elastin-Like Polypeptides (ELPs)-Aggregation-Induced-Emission (AIE) Conjugates for Temperature Sensing".MOLECULES 23.7(2018).
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Chen, Zhe]'s Articles
[Ding, Zhaoyang]'s Articles
[Zhang, Guangya]'s Articles
Baidu academic
Similar articles in Baidu academic
[Chen, Zhe]'s Articles
[Ding, Zhaoyang]'s Articles
[Zhang, Guangya]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Chen, Zhe]'s Articles
[Ding, Zhaoyang]'s Articles
[Zhang, Guangya]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.