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An Individual Nanocube-Based Plasmonic Biosensor for Real-Time Monitoring the Structural Switch of the Telomeric G-Quadruplex
Tian Y.1; Zhang L.1; Shen J.1; Wu L.1; He H.2; Ma D.-L.2; Leung C.-H.3; Wu W.4; Fan Q.1; Huang W.1,5; Wang L.1
2016
Source PublicationSmall
ISSN1613-6810
Volume12Issue:21Pages:2913-2920
Abstract

Promoted by the localized surface plasmon resonance nanotechnology, a simple and sensitive plasmonic aptamer nanosensor (nanoaptasensor) on an individual Au@Ag core-shell nanocube (Au@Ag NC) has been proposed for real-time monitoring of the formation process of G-quadruplex structures and label-free analysis of potassium ions (K+). In particular, the analysis of the thermodynamic parameters indicates that there are two types of binding states accompanied with a remarkable change of free energy (ΔG) in the sequential folding process of telomere DNA sequence. This nanoaptasensor has raised promising applications in monitoring the dynamic process of the structural switch of the G-quadruplex. 

KeywordCore-shell Nanocubes G-quadruplex Localized Surface Plasmon Resonance Nanoaptasensors, Biosensors
DOIhttps://doi.org/10.1002/smll.201600041
URLView the original
Indexed BySCIE
Language英语
WOS Research AreaChemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS SubjectChemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
WOS IDWOS:000378425000013
The Source to ArticleScopus
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Cited Times [WOS]:25   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorFan Q.; Wang L.
Affiliation1.Nanjing Univ Posts & Telecommun, Natl Jiangsu Synerget Innovat Ctr Adv Mat SICAM, Key Lab Organ Elect & Informat Displays, 9 Wenyuan Rd, Nanjing 210023, Jiangsu, Peoples R China
2.Hong Kong Baptist Univ, Dept Chem, Kowloon Tong, Hong Kong, Peoples R China
3.Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Taipa, Peoples R China
4.Nanjing Forestry Univ, Jiangsu Prov Key Lab Pulp & Paper Sci & Technol, Nanjing 210037, Jiangsu, Peoples R China
5.Nanjing Tech Univ, Natl Jiangsu Synerget Innovat Ctr Adv Mat SICAM, Key Lab Flexible Elect KLOFE, 30 South Puzhu Rd, Nanjing 211816, Jiangsu, Peoples R China
Recommended Citation
GB/T 7714
Tian Y.,Zhang L.,Shen J.,et al. An Individual Nanocube-Based Plasmonic Biosensor for Real-Time Monitoring the Structural Switch of the Telomeric G-Quadruplex[J]. Small,2016,12(21):2913-2920.
APA Tian Y..,Zhang L..,Shen J..,Wu L..,He H..,...&Wang L..(2016).An Individual Nanocube-Based Plasmonic Biosensor for Real-Time Monitoring the Structural Switch of the Telomeric G-Quadruplex.Small,12(21),2913-2920.
MLA Tian Y.,et al."An Individual Nanocube-Based Plasmonic Biosensor for Real-Time Monitoring the Structural Switch of the Telomeric G-Quadruplex".Small 12.21(2016):2913-2920.
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