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Siegesbeckia pubescens Makino inhibits Pam(3)CSK(4)-induced inflammation in RAW 264.7 macrophages through suppressing TLR1/TLR2-mediated NF-kappa B activation
Sang, Wei1; Zhong, Zhangfeng1,4; Linghu, Kegang1; Xiong, Wei1; Tse, Anfernee Kai Wing5; Cheang, Wai San1; Yu, Hua1,2,3,6; Wang, Yitao1,7
2018-07-05
Source PublicationCHINESE MEDICINE
ISSN1749-8546
Volume13
Abstract

Background: Siegesbeckia pubescens Makino (SP) is one of the important plant origins for the anti-inflammatory Chinese herbal medicine of Siegesbeckiae Herba. The current investigations indicated that the anti-inflammatory effects of SP were associated with the toll-like receptors (TLRs)-mediated nuclear factor-kB (NF-kB) and the mitogen-activated protein kinase (MAPK) signaling pathways.

KeywordSiegesbeckia Pubescens Makino Pam(3)Csk(4) Inflammation Toll-like Receptor 1/2 Nf-kappa b
DOIhttp://doi.org/10.1186/s13020-018-0193-x
URLView the original
Indexed BySCI
Language英语
WOS Research AreaIntegrative & Complementary Medicine ; Pharmacology & Pharmacy
WOS SubjectIntegrative & Complementary Medicine ; Pharmacology & Pharmacy
WOS IDWOS:000437441000001
PublisherBMC
The Source to ArticleWOS
Fulltext Access
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Cited Times [WOS]:2   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorYu, Hua; Wang, Yitao
Affiliation1.Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Macao, China.
2.HKBU Shenzhen Research Center, Shenzhen, Guangdong, China.
3.School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
4.Guangdong Key Laboratory for Research and Development of Natural Drugs, Guangdong Medical University, Zhanjiang, China
5.Academy for Advanced Interdisciplinary Studies, Southern University of Science and Technology, Shenzhen, Guangdong, China
6.Institute of Chinese Medical Sciences, University of Macau, Room 8008, Building N22, Avenida da Universidade, Taipa, Macao SAR, China
7.Institute of Chinese Medical Sciences, University of Macau, Room 1050, Building N22, Avenida da Universidade, Taipa, Macao SAR, China
First Author AffilicationInstitute of Chinese Medical Sciences
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Sang, Wei,Zhong, Zhangfeng,Linghu, Kegang,et al. Siegesbeckia pubescens Makino inhibits Pam(3)CSK(4)-induced inflammation in RAW 264.7 macrophages through suppressing TLR1/TLR2-mediated NF-kappa B activation[J]. CHINESE MEDICINE,2018,13.
APA Sang, Wei.,Zhong, Zhangfeng.,Linghu, Kegang.,Xiong, Wei.,Tse, Anfernee Kai Wing.,...&Wang, Yitao.(2018).Siegesbeckia pubescens Makino inhibits Pam(3)CSK(4)-induced inflammation in RAW 264.7 macrophages through suppressing TLR1/TLR2-mediated NF-kappa B activation.CHINESE MEDICINE,13.
MLA Sang, Wei,et al."Siegesbeckia pubescens Makino inhibits Pam(3)CSK(4)-induced inflammation in RAW 264.7 macrophages through suppressing TLR1/TLR2-mediated NF-kappa B activation".CHINESE MEDICINE 13(2018).
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