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Label-free luminescent switch-on probe for ochratoxin a detection using a G-quadruplex-selective iridium(III) complex
Lu L.; Wang M.; Liu L.-J.; Leung C.-H.; Ma D.-L.
2015
Source PublicationACS Applied Materials and Interfaces
ISSN19448244
Volume7Issue:15Pages:8313
AbstractA library of six luminescent Ir(III) complexes were synthesized and studied for their capacity to function as probes for G-quadruplex DNA. The novel Ir(III) complex 1 was discovered to be selective for G-quadruplex structures and was subsequently used for the construction of a label-free G-quadruplex-based ochratoxin A (OTA) sensing platform in aqueous solution. The assay exhibited linearity for OTA in the range of 0 to 60 nM (R2 = 0.9933), and the limit of detection for OTA was 5 nM. Furthermore, this assay was highly selective for OTA over its structurally related analogues. © 2015 American Chemical Society.
KeywordG-quadruplex iridium(III) complex label-free luminescent ochratoxin A
DOI10.1021/acsami.5b01702
URLView the original
Language英语
The Source to ArticleScopus
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Cited Times [WOS]:37   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
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GB/T 7714
Lu L.,Wang M.,Liu L.-J.,et al. Label-free luminescent switch-on probe for ochratoxin a detection using a G-quadruplex-selective iridium(III) complex[J]. ACS Applied Materials and Interfaces,2015,7(15):8313.
APA Lu L.,Wang M.,Liu L.-J.,Leung C.-H.,&Ma D.-L..(2015).Label-free luminescent switch-on probe for ochratoxin a detection using a G-quadruplex-selective iridium(III) complex.ACS Applied Materials and Interfaces,7(15),8313.
MLA Lu L.,et al."Label-free luminescent switch-on probe for ochratoxin a detection using a G-quadruplex-selective iridium(III) complex".ACS Applied Materials and Interfaces 7.15(2015):8313.
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