A phosphinate-based near-infrared fluorescence probe for imaging the superoxide radical anion in vitro and in vivo

doi:10.1039/c5cc09976e

UM > Institute of Chinese Medical Sciences

	A phosphinate-based near-infrared fluorescence probe for imaging the superoxide radical anion in vitro and in vivo
	Jianjian Zhang 1; Chuwen Li 2; Rui Zhang 1; Fengyuan Zhang 1; Wei Liu 1; Xiaoyan Liu 1; Simon Ming-Yuen Lee2 ; Haixia Zhang 1
	2016
Source Publication	Chemical Communications
ISSN	13597345
Volume	52 Issue:13 Pages:2679
Abstract	A novel near-infrared (NIR), turn-on fluorescence probe CyR containing a phosphinate group as a recognizing moiety for the selective detection of O2 - with a low limit of detection (LOD, 9.9 nM) was developed. CyR has good cell-membrane permeability, intracellular stability, and low cytotoxicity. In addition, we successfully applied the CyR to visualize O2 - in live zebrafish, mouse and, for the first time, in mouse liver.
DOI	10.1039/c5cc09976e
URL	View the original
Indexed By	SCIE ; IC
Language	英语
WOS Research Area	Chemistry
WOS Subject	Chemistry, Multidisciplinary
WOS ID	WOS:000369642800002
The Source to Article	Scopus
Fulltext Access	View Full-Text via DOI View Full-Text via Web of Science View Full-Text via Scopus
Citation statistics	Cited Times [WOS]:53 [WOS Record] [Related Records in WOS]
Document Type	Journal article
Collection	Institute of Chinese Medical Sciences
Corresponding Author	Haixia Zhang
Affiliation	1.State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization of Gansu Province and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China 2.State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macao, China
Recommended Citation GB/T 7714	Jianjian Zhang,Chuwen Li,Rui Zhang,et al. A phosphinate-based near-infrared fluorescence probe for imaging the superoxide radical anion in vitro and in vivo[J]. Chemical Communications,2016,52(13):2679.
APA	Jianjian Zhang.,Chuwen Li.,Rui Zhang.,Fengyuan Zhang.,Wei Liu.,...&Haixia Zhang.(2016).A phosphinate-based near-infrared fluorescence probe for imaging the superoxide radical anion in vitro and in vivo.Chemical Communications,52(13),2679.
MLA	Jianjian Zhang,et al."A phosphinate-based near-infrared fluorescence probe for imaging the superoxide radical anion in vitro and in vivo".Chemical Communications 52.13(2016):2679.

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