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A novel strategy with standardized reference extract qualification and single compound quantitative evaluation for quality control of Panax notoginseng used as a functional food
Li S.P.1; Qiao C.F.1; Chen Y.W.1; Zhao J.1; Cui X.M.2; Zhang Q.W.1; Liu X.M.1; Hu D.J.1
2013
Source PublicationJournal of Chromatography A
ISSN0021-9673
Volume1313Pages:302
Abstract

Root of Panax notoginseng (Burk.) F.H. Chen (Sanqi in Chinese) is one of traditional Chinese medicines (TCMs) based functional food. Saponins are the major bioactive components. The shortage of reference compounds or chemical standards is one of the main bottlenecks for quality control of TCMs. A novel strategy, i.e. standardized reference extract based qualification and single calibrated components directly quantitative estimation of multiple analytes, was proposed to easily and effectively control the quality of natural functional foods such as Sanqi. The feasibility and credibility of this methodology were also assessed with a developed fast HPLC method. Five saponins, including ginsenoside Rg1, Re, Rb1, Rd and notoginsenoside R1 were rapidly separated using a conventional HPLC in 20min. The quantification method was also compared with individual calibration curve method. The strategy is feasible and credible, which is easily and effectively adapted for improving the quality control of natural functional foods such as Sanqi. 

KeywordFunctional Food Panax Notoginseng Quality Control Standardized Reference Extract
DOIhttp://doi.org/10.1016/j.chroma.2013.07.025
URLView the original
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS SubjectBiochemical Research Methods ; Chemistry, Analytical
WOS IDWOS:000325673200030
The Source to ArticleScopus
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Cited Times [WOS]:42   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorLi S.P.
Affiliation1.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao
2.Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China
First Author AffilicationInstitute of Chinese Medical Sciences
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Li S.P.,Qiao C.F.,Chen Y.W.,et al. A novel strategy with standardized reference extract qualification and single compound quantitative evaluation for quality control of Panax notoginseng used as a functional food[J]. Journal of Chromatography A,2013,1313:302.
APA Li S.P..,Qiao C.F..,Chen Y.W..,Zhao J..,Cui X.M..,...&Hu D.J..(2013).A novel strategy with standardized reference extract qualification and single compound quantitative evaluation for quality control of Panax notoginseng used as a functional food.Journal of Chromatography A,1313,302.
MLA Li S.P.,et al."A novel strategy with standardized reference extract qualification and single compound quantitative evaluation for quality control of Panax notoginseng used as a functional food".Journal of Chromatography A 1313(2013):302.
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