UM  > 健康科學學院
T1rho and T2 relaxation times for lumbar disc degeneration: An in vivo comparative study at 3.0-Tesla MRI
Wang Y.-X.J.1; Zhao F.1; Griffith J.F.1; Mok G.S.P.2; Leung J.C.S.3; Ahuja A.T.1; Yuan J.1
2013
Source PublicationEuropean Radiology
ISSN9387994
Volume23Issue:1Pages:228
Abstract

Objective: To determine the relative performance of T1rho and T2 relaxation times in disc degeneration assessment. Methods: Lumbar sagittal MRI was performed at 3 T in 52 subjects. With a spin-lock frequency of 500Hz, T1rho was measured using a rotary echo spin-lock pulse embedded in a three-dimensional (3D) balanced fast field echo sequence. A multi-echo TSE sequence was used for T2 mapping. Regions of interest (ROIs) were drawn over the T1rho and T2 maps, including nucleus pulposus (NP) and annulus fibrosus (AF). Eight- and five-level disc degeneration semi-quantitative grading was performed. Results: For NP, T1rho and T2 decreased quadratically with disc degeneration grades and had no significant trend difference (P = 0.40). For AF, T1rho decreased linearly as the disc degenerated and had a slope of -3.02 and -4.56 for eight- and five-level gradings respectively; while the slopes for T2 values were -1.43 and -1.84 respectively, being significantly flatter than those of T1rho (P < 0.001). There was no significant difference in T1rho and T2 values for both NP and AF among discs of grade 5/8 to 8/8 degeneration. Conclusion: T1rho is better suited for evaluating AF in degenerated disc than T2. In NP, T1rho and T2 decrease in a similar pattern following disc degeneration. Key Points: • MRI provides unique information about the lumbar disc nucleus pulposus • Both T1rho and T2 relaxation times decrease similarly following disc degeneration • AF T1rho relaxation times decrease progressively faster than T2 relaxation times • T2 and T1rho relaxation times do not reduce further by disc-space narrowing © 2012 European Society of Radiology.

KeywordAnnulus Fibrosus Degeneration Disc Magnetic Resonance Imaging Nucleus Pulposus
DOIhttps://doi.org/10.1007/s00330-012-2591-2
URLView the original
Indexed BySCI
Language英语
WOS Research AreaRadiology, Nuclear Medicine & Medical Imaging
WOS SubjectRadiology, Nuclear Medicine & Medical Imaging
WOS IDWOS:000312324500029
The Source to ArticleScopus
Fulltext Access
Citation statistics
Cited Times [WOS]:57   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Corresponding AuthorWang Y.-X.J.
Affiliation1.Department of Imaging and Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
2.Department of Electrical and Electronics Engineering, University of Macau, Taipa, Macau SAR, China
3.Jockey Club Centre for Osteoporosis Care and Control, School of Public Health and Primary Care, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
Recommended Citation
GB/T 7714
Wang Y.-X.J.,Zhao F.,Griffith J.F.,et al. T1rho and T2 relaxation times for lumbar disc degeneration: An in vivo comparative study at 3.0-Tesla MRI[J]. European Radiology,2013,23(1):228.
APA Wang Y.-X.J..,Zhao F..,Griffith J.F..,Mok G.S.P..,Leung J.C.S..,...&Yuan J..(2013).T1rho and T2 relaxation times for lumbar disc degeneration: An in vivo comparative study at 3.0-Tesla MRI.European Radiology,23(1),228.
MLA Wang Y.-X.J.,et al."T1rho and T2 relaxation times for lumbar disc degeneration: An in vivo comparative study at 3.0-Tesla MRI".European Radiology 23.1(2013):228.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Wang Y.-X.J.]'s Articles
[Zhao F.]'s Articles
[Griffith J.F.]'s Articles
Baidu academic
Similar articles in Baidu academic
[Wang Y.-X.J.]'s Articles
[Zhao F.]'s Articles
[Griffith J.F.]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Wang Y.-X.J.]'s Articles
[Zhao F.]'s Articles
[Griffith J.F.]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.