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Simultaneous determination of nine saponins from Panax notoginseng using HPLC and pressurized liquid extraction
Wan J.B.1,2; Lai C.M.1; Li S.P.1; Lee M.Y.1; Kong L.Y.2; Wang Y.T.1
2006
Source PublicationJournal of Pharmaceutical and Biomedical Analysis
ISSN7317085
Volume41Issue:1Pages:274
Abstract

A HPLC and pressurized liquid extraction (PLE) method was developed for simultaneous determination of nine saponins, including notoginsenoside R1, ginsenoside Rg1, Re, Rf, Rb1, Rc, Rb2, Rb3 and Rd in Panax notoginseng. The analysis was performed on C18 column with water-acetonitrile gradient elution and the investigated saponins were authenticated by comparing retention time and mass spectra with their reference compounds. Several methods including PLE, ultrasonication, soxhlet extraction and immersion were used for sample preparation and their extraction efficiency was compared. The results showed that PLE has the highest extraction efficiency and repeatability, which would be valuable on standardization of sample preparation for quality control of Chinese medicines. The developed HPLC and PLE is an effective approach for simultaneously quantitative determination of sapoinins in P. notoginseng, which could be used for quality control of P. notoginseng and its preparations. © 2005 Elsevier B.V. All rights reserved.

KeywordGinsenoside Notoginsenoside Panax Notoginseng Pressurized Liquid Extraction
DOIhttps://doi.org/10.1016/j.jpba.2005.10.023
URLView the original
Indexed BySCI
Language英语
WOS Research AreaChemistry ; Pharmacology & Pharmacy
WOS SubjectChemistry, Analytical ; Pharmacology & Pharmacy
WOS IDWOS:000236655100039
The Source to ArticleScopus
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Cited Times [WOS]:64   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorLi S.P.; Wang Y.T.
Affiliation1.Institute of Chinese Medical Sciences, University of Macau, Taipa, Macau, China
2.Department of Phytochemistry, China Pharmaceutical University, Nanjing 210038, China
First Author AffilicationInstitute of Chinese Medical Sciences
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Wan J.B.,Lai C.M.,Li S.P.,et al. Simultaneous determination of nine saponins from Panax notoginseng using HPLC and pressurized liquid extraction[J]. Journal of Pharmaceutical and Biomedical Analysis,2006,41(1):274.
APA Wan J.B.,Lai C.M.,Li S.P.,Lee M.Y.,Kong L.Y.,&Wang Y.T..(2006).Simultaneous determination of nine saponins from Panax notoginseng using HPLC and pressurized liquid extraction.Journal of Pharmaceutical and Biomedical Analysis,41(1),274.
MLA Wan J.B.,et al."Simultaneous determination of nine saponins from Panax notoginseng using HPLC and pressurized liquid extraction".Journal of Pharmaceutical and Biomedical Analysis 41.1(2006):274.
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