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GC-MS fingerprint of Pogostemon cablin in China
Hu L.F.1; Li S.P.1; Cao H.2; Liu J.J.1; Gao J.L.1; Yang F.Q.1; Wang Y.T.1
2006
Source PublicationJournal of Pharmaceutical and Biomedical Analysis
ISSN7317085
Volume42Issue:2Pages:200
Abstract

Pogostemon cablin, originating in Malaysia and India, is cultivated in southern China including Guangdong and Hainan Province, which was called GuangHuoXiang to differentiate it from the HuoXiang of the north, the species Agastache rugosa, that it resembles. Essential oil of P. cablin mainly contributes to the pharmacological activities and the therapeutic properties of the essential oils are directly correlated with their qualitative and quantitative composition. For controlling the quality, standard fingerprint of P. cablin collected from different regions was developed by using GC-MS. Nine compounds including β-patchoulene, caryophyllene, α-guaiene, seychellene, β-guaiene, δ-guaiene, spathulenol, patchouli alcohol and pogostone were identified among 10 main peaks in P. cablin. Hierarchical clustering analysis based on characteristics of 10 investigated peaks in GC profiles showed that 18 samples were divided into three main clusters, patchouliol-type, pogostone-type and an interim-type, which was the one between the two chemotypes. The simulative mean chromatogram for the three types P. cablin was generated using the Computer Aided Similarity Evaluation System. The fingerprint can help to distinguish the substitute or adulterant, and further assess the differences of P. cablin grown in various areas of China. © 2005 Elsevier B.V. All rights reserved.

KeywordGc-ms Fingerprint Patchouli Alcohol Pogostemon Cablin Pogostone Quality Control
DOIhttp://doi.org/10.1016/j.jpba.2005.09.015
URLView the original
Indexed BySCI
Language英语
WOS Research AreaChemistry ; Pharmacology & Pharmacy
WOS SubjectChemistry, Analytical ; Pharmacology & Pharmacy
WOS IDWOS:000241090100007
The Source to ArticleScopus
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Cited Times [WOS]:65   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorLi S.P.; Wang Y.T.
Affiliation1.Institute of Chinese Medical Sciences, University of Macau, Taipa, Macau SAR, China
2.National Engineering Research Center for Modernization of Traditional Chinese Medicine, Zhuhai, China
First Author AffilicationInstitute of Chinese Medical Sciences
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Hu L.F.,Li S.P.,Cao H.,et al. GC-MS fingerprint of Pogostemon cablin in China[J]. Journal of Pharmaceutical and Biomedical Analysis,2006,42(2):200.
APA Hu L.F..,Li S.P..,Cao H..,Liu J.J..,Gao J.L..,...&Wang Y.T..(2006).GC-MS fingerprint of Pogostemon cablin in China.Journal of Pharmaceutical and Biomedical Analysis,42(2),200.
MLA Hu L.F.,et al."GC-MS fingerprint of Pogostemon cablin in China".Journal of Pharmaceutical and Biomedical Analysis 42.2(2006):200.
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