UM
Iridium-based probe for luminescent nitric oxide monitoring in live cells
Wu, Chun; Wu, Ke-Jia; Kang, Tian-Shu; Wang, Hui-Min David; Leung, Chung-Hang; Liu, Jin-Biao; Ma, Dik-Lung
2018-08-20
Source PublicationSCIENTIFIC REPORTS
ISSN2045-2322
Volume8
AbstractNitric oxide (NO) is an intra- and extracellular messenger with important functions during human physiology process. A long-lived luminescent iridium(III) complex probe 1 has been designed and synthesized for the monitoring of NO controllably released from sodium nitroprusside (SNP). Probe 1 displayed a 15-fold switch-on luminescence in the presence of SNP at 580 nm. The probe exhibited a linear response towards SNP between 5 to 25 mu M with detection limit at 0.18 mu M. Importantly, the luminescent switch-on detection of NO in HeLa cells was demonstrated. Overall, complex 1 has the potential to be applied for NO tracing in complicated cellular environment.
DOI10.1038/s41598-018-30991-9
URLView the original
Indexed BySCI
Language英语
WOS Research AreaScience & Technology - Other Topics
WOS SubjectMultidisciplinary Sciences
WOS IDWOS:000442131600025
PublisherNATURE PUBLISHING GROUP
The Source to ArticleWOS
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Citation statistics
Cited Times [WOS]:5   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Recommended Citation
GB/T 7714
Wu, Chun,Wu, Ke-Jia,Kang, Tian-Shu,et al. Iridium-based probe for luminescent nitric oxide monitoring in live cells[J]. SCIENTIFIC REPORTS,2018,8.
APA Wu, Chun.,Wu, Ke-Jia.,Kang, Tian-Shu.,Wang, Hui-Min David.,Leung, Chung-Hang.,...&Ma, Dik-Lung.(2018).Iridium-based probe for luminescent nitric oxide monitoring in live cells.SCIENTIFIC REPORTS,8.
MLA Wu, Chun,et al."Iridium-based probe for luminescent nitric oxide monitoring in live cells".SCIENTIFIC REPORTS 8(2018).
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