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An insight into anti-diabetic properties of dietary phytochemicals
Vinayagam, Ramachandran1; Xiao, Jianbo2; Xu, Baojun1
2017-06
Conference Name2nd International Symposium on Phytochemicals in Medicine and Food (ISPMF)
Source PublicationPHYTOCHEMISTRY REVIEWS
Volume16
Issue3
Pages535-553
Conference DateAPR 07-10, 2017
Conference PlaceFuzhou, PEOPLES R CHINA
Publication PlaceVAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS
PublisherSPRINGER
Abstract

Diabetes are a serious metabolic diseases characterized by abnormally increased plasma glucose levels. Botanical food products have been used for combating human diseases for thousands of years, since they exhibit a wide range of biological properties that can be exploited for medical application. Phytochemicals from foods, including flavonoids, monoterpenes, terpenoids, stilbenes, lignans, coumarins, alkaloids, and others, have been proposed as effective supplements for diabetes management and prevention of its long-term complications in vitro and in vivo. The mechanism of antidiabetic activity of dietary phytochemicals could be summarized as: stimulation of insulin secretion from pancreatic beta-cell, reduction of insulin resistance and increasing of insulin sensitivity, stimulation of glycogenesis and hepatic glycolysis, activation of PPAR gamma, anti-inflammatory and antioxidant effects, inhibition of alpha-amylase, beta-galactocidase and alpha-glucocidase, and inhibition intestinal absorption of glucose. Therefore the anti-diabetic effects and their mechanism of action of phytochemicals from botanical foods used traditionally in the treatment of diabetes mellitus are critically reviewed.

KeywordDiabetes Mellitius Botanical Foods Phytochemicals Anti-diabetic Mechanism
DOI10.1007/s11101-017-9496-2
URLView the original
Indexed BySCI ; CPCI
Language英语
WOS Research AreaPlant Sciences
WOS SubjectPlant Sciences
WOS IDWOS:000403018000008
The Source to ArticleWOS
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Cited Times [WOS]:29   [WOS Record]     [Related Records in WOS]
Document TypeConference paper
CollectionInstitute of Chinese Medical Sciences
Affiliation1.Hong Kong Baptist Univ, Beijing Normal Univ, United Int Coll, Food Sci & Technol Program, Zhuhai 519085, Guangdong, Peoples R China
2.Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Taipa, Macau, Peoples R China
Recommended Citation
GB/T 7714
Vinayagam, Ramachandran,Xiao, Jianbo,Xu, Baojun. An insight into anti-diabetic properties of dietary phytochemicals[C]. VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS:SPRINGER,2017:535-553.
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