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Seasonal dynamics of the phytochemical constituents and bioactivities of extracts from Stenoloma chusanum (L.) Ching
Wu, Siqi; Li, Jing; Wang, Quanxi; Cao, Hui; Cao, Jianguo; Xiao, Jianbo
2017-10
Conference NameFOOD AND CHEMICAL TOXICOLOGY
Volume108
Pages458-466
Publication PlaceTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
PublisherPERGAMON-ELSEVIER SCIENCE LTD
AbstractStenoloma chusanum is a traditional Chinese medicinal herb with a very high total flavonoid content (TFC). The seasonal dynamics of the TFC and total phenolic content (TPC) in S. chusanum, as well as antioxidant activity, were investigated. The TFC and TPC showed clear seasonal dynamics, reaching their maxima (24.63 +/- 1.34% and 9.58 +/- 0.41%, respectively) in February. The TFC and TPC in the aerial parts of the plant were much higher than those in the subterranean parts; however, the antioxidant activities of the extracts from the subterranean parts were slightly higher than those from the aerial parts. Moreover, the extracts exhibited higher inhibition against tyrosinase than against arbutin (the positive control). The extract from S. chusanum collected in February was associated with the highest proliferation and apoptosis of K562 cells. The phytochemicals in the extract were analyzed using LC-MS, and were found to comprise of 12 flavonoids, five alkaloids, one sesquiterpenoid and one phenypropanoid. In conclusion, S. chusanum exhibits multiple bioactivities; these results could contribute to the therapeutic application of the plants in indigenous medicine. (C) 2016 Elsevier Ltd. All rights reserved.
KeywordStenoloma chusanum Flavonoids Antioxidant activity Anti-tumor activity Anti-tyrosinase activity
DOI10.1016/j.fct.2016.10.003
URLView the original
Indexed BySCI ; CPCI
Language英语
WOS Research AreaFood Science & Technology ; Toxicology
WOS SubjectFood Science & Technology ; Toxicology
WOS IDWOS:000413135100011
The Source to ArticleWOS
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Cited Times [WOS]:9   [WOS Record]     [Related Records in WOS]
Document TypeConference paper
CollectionUniversity of Macau
Recommended Citation
GB/T 7714
Wu, Siqi,Li, Jing,Wang, Quanxi,et al. Seasonal dynamics of the phytochemical constituents and bioactivities of extracts from Stenoloma chusanum (L.) Ching[C]. THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND:PERGAMON-ELSEVIER SCIENCE LTD,2017:458-466.
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