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Prescription of antipsychotic and concomitant medications for adult Asian schizophrenia patients: Findings of the 2016 Research on Asian Psychotropic Prescription Patterns (REAP) survey
Min Dong1; Liang-Nan Zeng2,3,4; Qinge Zhang5; Shu-Yu Yang6; Lian-Yu Chen7; Eunice Najoan8; Roy Abraham Kallivayalil9; Kittisak Viboonma10; Ruzita Jamaluddin11; Afzal Javed12; Duong Thi Quynh Hoa13; Hitoshi Iida14; Kang Sim15; Thiha Swe16; Yan-Ling He17; Yongchon Park18; Helal Uddin Ahmed19; Angelo De Alwis20; Helen F.K. Chiu21; Norman Sartorius22; Chay-Hoon Tan23; Mian-Yoon Chong24; Naotaka Shinfuku25; Shih-Ku Lin7,26; Ajit Avasthi27; Sandeep Grover27; Chee H. Ng28; Gabor S. Ungvari29,30; Yu-Tao Xiang2,3
2019-10
Source PublicationASIAN JOURNAL OF PSYCHIATRY
ISSN1876-2018
Volume45Pages:74-80
AbstractObjective Regular surveys are important to monitor the use of psychotropic medications in clinical practice. This study examined the psychotropic prescription patterns in adult Asian schizophrenia patients based on the data of the Research on Asian Psychotropic Prescription (REAP) 2016 survey. Methods : This cross-sectional survey across 15 Asian countries/territories collected socio-demographic and clinical data with standardized procedures between March and May 2016. The socio-demographic and clinical characteristics of the patients were recorded with a standardized questionnaire. Results Altogether 3,537 adult patients with schizophrenia were consecutively screened and enrolled in the survey. The mean age was 38.66 ± 11.55 years and 59.7% of the sample were male. The mean dose of antipsychotics in chlorpromazine equivalents (CPZeq) was 424 ± 376 mg/day; 31.3% and 80.8% received first- and second- generation antipsychotics, respectively and 42.6% had antipsychotic polypharmacy, 11.7% had antidepressants, 13.7% had mood stabilizers, 27.8% had benzodiazepines, and 45.6% had anticholinergics. Conclusions Psychotropic prescription patterns in Asian adult patients with schizophrenia varied across countries. Regular surveys on psychotropic medications for schizophrenia are important to monitor pharmacotherapy practice in Asia.
KeywordAntipsychotics Asia Schizophrenia Prescription Patterns
DOI10.1016/j.ajp.2019.08.010
Indexed BySCI
Language英语
WOS Research AreaPsychiatry
WOS SubjectPsychiatry
WOS IDWOS:000491464800018
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Cited Times [WOS]:1   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Affiliation1.Guangdong Mental Health Center, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China
2.Department of Psychiatry, Hanyang University, Seoul, Republic of Korea
3.National Institute of Mental Health, Dhaka, Bangladesh
4.National Institute of Mental Health, Angoda, Sri Lanka
5.Department of Psychiatry, Chinese University of Hong Kong, Hong Kong SAR, China
6.Association for the Improvement of Mental Health Programs, Geneva, Switzerland
7.Department of Pharmacology, National University of Singapore, Singapore
8.Chiayi Chang Gung Memorial Hospital and School of Medicine, Chang Gung University, Chiayi, Taiwan
9.International Center for Medical Research, Kobe University School of Medicine, Kobe, Japan
10.Department of Psychiatry, School of Medicine, Taipei Medical University, Taipei, Taiwan
11.Department of Psychiatry, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
12.Department of Psychiatry, University of Melbourne, Melbourne, Victoria, Australia
13.University of Notre Dame Australia, Fremantle, Australia
14.Division of Psychiatry, Medical School, University of Western Australia, Perth, Australia
15.Unit of Psychiatry, Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macao SAR, China
16.Center for Cognition and Brain Sciences, Faculty of Health Sciences, University of Macau, Macao SAR, China
17.Department of Neurosurgery, The Affiliated Hospital of Southwest Medical University, Neurosurgery Clinical Medical Research Center of Sichuan Province, Academician (Expert) Workstation of Sichuan Province, Sichuan, China
18.The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders Beijing Anding Hospital & the Advanced Innovation Center for Human Brain Protection, Capital Medical University, School of Mental Health, Beijing, China
19.Department of Pharmacy, Taipei City Hospital, Taipei, Taiwan
20.Department of Psychiatry, Taipei City Hospital and Psychiatric Center, Taipei, Taiwan
21.Mintoharjo Hospital, Jakarta, Indonesia
22.Pushpagiri Institute of Medical Sciences, Tiruvalla, Kerala, India
23.Suanprung Psychiatric Hospital, Chian Mai, Thailand
24.Department of Psychiatry & Mental Health, Hospital Tuanku Fauziah, Kangar, Perlis, Malaysia
25.Pakistan Psychiatric Research Centre, Fountain House, Lahore, Pakistan
26.Thanh Hoa Provincial Psychiatric Hospital, Thanh Hoa, Vietnam
27.Department of Psychiatry, Faculty of Medicine, Fukuoka University, Fukuoka, Japan
28.Institute of Mental Health, Buangkok Green Medical Park, Singapore
29.Department of Mental Health, University of Medicine, Magway, Myanmar
30.Department of Psychiatric Epidemiology, Shanghai Mental Health Center, Shanghai, China
Recommended Citation
GB/T 7714
Min Dong,Liang-Nan Zeng,Qinge Zhang,et al. Prescription of antipsychotic and concomitant medications for adult Asian schizophrenia patients: Findings of the 2016 Research on Asian Psychotropic Prescription Patterns (REAP) survey[J]. ASIAN JOURNAL OF PSYCHIATRY,2019,45:74-80.
APA Min Dong.,Liang-Nan Zeng.,Qinge Zhang.,Shu-Yu Yang.,Lian-Yu Chen.,...&Yu-Tao Xiang.(2019).Prescription of antipsychotic and concomitant medications for adult Asian schizophrenia patients: Findings of the 2016 Research on Asian Psychotropic Prescription Patterns (REAP) survey.ASIAN JOURNAL OF PSYCHIATRY,45,74-80.
MLA Min Dong,et al."Prescription of antipsychotic and concomitant medications for adult Asian schizophrenia patients: Findings of the 2016 Research on Asian Psychotropic Prescription Patterns (REAP) survey".ASIAN JOURNAL OF PSYCHIATRY 45(2019):74-80.
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