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Discrimination of three Siegesbeckiae Herba species using UPLC-QTOF/MS-based metabolomics approach
Tao, Hong-Xun1; Xiong, Wei1; Zhao, Guan-Ding1; Peng, Yu1; Zhong, Zhang-Feng1; Xu, Liang5; Duan, Ran4; Tsim, Karl W. K.4; Yu, Hua1,2,3; Wang, Yi-Tao1
2018-09
Conference Name3rd International Symposium on Phytochemicals in Medicine and Food (ISPMF)
Source PublicationFOOD AND CHEMICAL TOXICOLOGY
Volume119
Pages400-406
Conference DateAUG 25-30, 2018
Conference PlaceKunming, PEOPLES R CHINA
Publication PlaceTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
PublisherPERGAMON-ELSEVIER SCIENCE LTD
Abstract

The plant origin is one of the most important factors for the quality control of traditional Chinese medicines (TCMs) and highly affected on their safety and effectiveness in clinical applications. Multi-origin has been widely observed for many TCMs. Siegesbeckiae Herba (SH) is a traditional anti-rheumatic TCM which is originated from the plants of Siegesbeckia pubescens Makino (SP), S. orientalis L. (SO), and S. glabrescens Makino (SG). In the present study, an UPLC-QTOF/MS method were validated and successfully applied for the determination of the chemical profiles in the three SH species. The data were statistical analyzed with the OPLS-DA analysis and One Way ANOVA F-test. Obvious differences in chemistry were observed in different SH species and 40 components were identified. Finally, 6 components were selected as potential chemical markers for the discrimination of SP, SO and SG based on the characteristic distribution in individual SH species.

KeywordMetabolomics Traditional Chinese Medicines Multi-origin Herbs Siegesbeckiae Herba Species Uplc-qtof/ms
DOIhttp://doi.org/10.1016/j.fct.2017.12.068
URLView the original
Indexed BySCI ; CPCI
Language英语
WOS Research AreaFood Science & Technology ; Toxicology
WOS SubjectFood Science & Technology ; Toxicology
WOS IDWOS:000443664200048
The Source to ArticleWOS
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Cited Times [WOS]:4   [WOS Record]     [Related Records in WOS]
Document TypeConference paper
CollectionInstitute of Chinese Medical Sciences
Affiliation1.Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Macao Special Administrative Region, China
2.HKBU Shenzhen Research Center, Shenzhen, Guangdong, China
3.School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong Special Administrative Region, China
4.Division of Life Science, Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong Special Administrative Region, China
5.School of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, China
First Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Tao, Hong-Xun,Xiong, Wei,Zhao, Guan-Ding,et al. Discrimination of three Siegesbeckiae Herba species using UPLC-QTOF/MS-based metabolomics approach[C]. THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND:PERGAMON-ELSEVIER SCIENCE LTD,2018:400-406.
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