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Trends involving monoclonal antibody (mAb) research and commercialization: A scientometric analysis of IMS Lifecycle R&D Focus Database (1980-2016)
Lai, YF1; Suo, SZ1; Wang, RB1; Kong, XJ1; Hu, YJ1; Tang, DS2; Shi, HH1; Chen, SQ1; Hu, H1
2018
Source PublicationHUMAN VACCINES & IMMUNOTHERAPEUTICS
ISSN2164-5515
Volume14Issue:4Pages:847-855
AbstractThis article aims to explore the trends of monoclonal antibodies (mAbs) research and commercialization, mainly to examine the development trajectories by a contrastive exploration of successful and unsuccessful mAb. This work is based on two sets of R&D project reports, consisting of 517 discontinued mAb project reports and 64 marketed mAb project reports, from IMS Lifecycle R&D Focus. The analysis of drug development processes will provide the basic evidences of mAb technology commercialization. We examined the mAb research and commercialization from three perspectives: (1) Countries with mAb research activity; (2) Organizations participating in mAb research and development; and (3) Clusters of keywords (indication and class description) regarding mAb. The technology factor, the market factor and the abilities of participating firms to pursue commercialization were analyzed. Through data analysis, we have discovered that the research and development on mAb has reached a mature and diversified stage.
KeywordTechnology Commercialization Citespace Ims Mab Monoclonal Antibody
DOI10.1080/21645515.2017.1420445
Indexed BySCI
Language英语
WOS Research AreaImmunology
WOS SubjectBiotechnology & Applied Microbiology
WOS IDWOS:000429600000017
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Cited Times [WOS]:1   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.State Key Laboratory of Quality Research in Chinese Medicine , Institute of Chinese Medical Sciences, University of Macau , Macao , China.
2.School of Economics and Management, Beijing Jiaotong University , Beijing , China.
First Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Lai, YF,Suo, SZ,Wang, RB,et al. Trends involving monoclonal antibody (mAb) research and commercialization: A scientometric analysis of IMS Lifecycle R&D Focus Database (1980-2016)[J]. HUMAN VACCINES & IMMUNOTHERAPEUTICS,2018,14(4):847-855.
APA Lai, YF.,Suo, SZ.,Wang, RB.,Kong, XJ.,Hu, YJ.,...&Hu, H.(2018).Trends involving monoclonal antibody (mAb) research and commercialization: A scientometric analysis of IMS Lifecycle R&D Focus Database (1980-2016).HUMAN VACCINES & IMMUNOTHERAPEUTICS,14(4),847-855.
MLA Lai, YF,et al."Trends involving monoclonal antibody (mAb) research and commercialization: A scientometric analysis of IMS Lifecycle R&D Focus Database (1980-2016)".HUMAN VACCINES & IMMUNOTHERAPEUTICS 14.4(2018):847-855.
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