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Dual stimuli-responsive bispillar[5]arene-based nanoparticles for precisely selective drug delivery in cancer cells
Qian Cheng1; Kun-Xu Teng2; Yuan-Fu Ding1; Ludan Yue1; Qing-Zheng Yang2; Ruibing Wang1
2019-02
Source PublicationCHEMICAL COMMUNICATIONS
ISSN1359-7345
Volume55Issue:16Pages:2340-2343
Abstract

Paclitaxel-loaded nanoparticles based on a bispillar[5]arene compound were successfully developed using a microemulsion method for the first time. The nanoparticles exhibited dual stimuli-responsiveness towards both spermine and glutathione, allowing precisely selective drug release in lung cancer cells that overexpress both stimuli.

DOI10.1039/c8cc09432b
Indexed BySCI
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000459022300019
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Cited Times [WOS]:8   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorRuibing Wang
Affiliation1.State Key Laboratory of Quality Research in Chinese Medicine, Institute of ChineseMedical Sciences, University of Macau, Taipa, Macau SAR, China
2.Key Laboratory of Radiopharmaceuticals, Ministry of Education, College ofChemistry, Beijing Normal University, Beijing 100875, P. R. China
First Author AffilicationUniversity of Macau
Corresponding Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Qian Cheng,Kun-Xu Teng,Yuan-Fu Ding,et al. Dual stimuli-responsive bispillar[5]arene-based nanoparticles for precisely selective drug delivery in cancer cells[J]. CHEMICAL COMMUNICATIONS,2019,55(16):2340-2343.
APA Qian Cheng,Kun-Xu Teng,Yuan-Fu Ding,Ludan Yue,Qing-Zheng Yang,&Ruibing Wang.(2019).Dual stimuli-responsive bispillar[5]arene-based nanoparticles for precisely selective drug delivery in cancer cells.CHEMICAL COMMUNICATIONS,55(16),2340-2343.
MLA Qian Cheng,et al."Dual stimuli-responsive bispillar[5]arene-based nanoparticles for precisely selective drug delivery in cancer cells".CHEMICAL COMMUNICATIONS 55.16(2019):2340-2343.
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