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Iridium(III) Complexes Targeting Apoptotic Cell Death in Cancer Cells
Ma, DL1; Wu, C1; Wu, KJ2; Leung, CH2
2019
Source PublicationMOLECULES
ISSN1420-3049
Volume24Issue:15
AbstractTargeting apoptosis is a principal strategy in the design of anticancer drugs. In recent years, non-platinum-based scaffolds have been exploited as viable candidates for the exploitation of anticancer agents with potentially lower toxicity than the widely used cisplatin analogues. This review highlights the latest advances in developing iridium(III) complexes as anticancer agents that act particularly via targeting apoptotic cell death in cancer cells.
KeywordIridium(Iii) Complex Cancer Mitochondria Apoptosis
DOI10.3390/molecules24152739
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS SubjectBiochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS IDWOS:000482441100062
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Cited Times [WOS]:5   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.Hong Kong Baptist Univ, Fac Sci, Dept Chem, Kowloon, Hong Kong 999077, Peoples R China
2.University of Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Macau 999078, Macau, Peoples R China
Recommended Citation
GB/T 7714
Ma, DL,Wu, C,Wu, KJ,et al. Iridium(III) Complexes Targeting Apoptotic Cell Death in Cancer Cells[J]. MOLECULES,2019,24(15).
APA Ma, DL,Wu, C,Wu, KJ,&Leung, CH.(2019).Iridium(III) Complexes Targeting Apoptotic Cell Death in Cancer Cells.MOLECULES,24(15).
MLA Ma, DL,et al."Iridium(III) Complexes Targeting Apoptotic Cell Death in Cancer Cells".MOLECULES 24.15(2019).
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