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Comparison of Antioxidant Activity and Main Active Compounds Among Different Parts of Alpinia officinarum Hance Using High-Performance Thin Layer Chromatography-Bioautography
Wan-Xin Zhang1; In-Cheng Chao1; De-Jun Hu1; Farid Shakerian1; Liya Ge2; Xiao Liang3; Ying Wang1; Jing Zhao1; Shao-Ping Li1
2019-06
Source PublicationJOURNAL OF AOAC INTERNATIONAL
ISSN1060-3271
Volume102Issue:3Pages:726-733
Abstract

Background: Alpinia officinarum Hance (ginger family) is an important Chinese medicine, especially in Southern China. Objective: A simple and effective high-performance thin-layer chromatography coupled with 2, 2-diphenyl-1-picrylhydrazyl bioautography (HPTLC-DPPH) and electrospray ionization quadrupole time-of-flight tandem mass spectrometry (ESI-Q-TOF-MS/MS) method was developed for the bioactivity-based quality control of A. officinarum. Methods: The HPTLC-DPPH and ESI-Q-TOF-MS/MS were applied for the analysis of different parts of A. officinarum after using methanol extraction for 23 batches of taproot, four batches of aerial, and three batches of fibril parts. Results: The systematic evaluation showed that similar components in taproot and aerial parts make the major antioxidant activity. However, based on our evaluation, the antioxidant ability of the aerial parts is lower than the taproot parts. There is also a significant difference (P < 0.05) between taproot and fibril parts of the root. The chemical structures of compounds with the antioxidant capacity were tentatively identified as 5R-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenyl-3-heptanone (band 1), kaempferide (band 2), and galangin (band 3) based on ESI-Q-TOF-MS/MS analytical results and further confirmed by standards. Conclusions: This identification indicated that two flavonoid compounds and one diarylheptanoid compound possessed high potentials to be used as the antioxidant biomarkers for the quality control of A. officinarum. Highlights: The comparison of different parts could be considered as guidelines for the usage of A. officinarum.

KeywordComponents Quantification Flavonoids Rhizome
DOI10.5740/jaoacint.18-0307
Indexed BySCI
Language英语
WOS Research AreaChemistry ; Food Science & Technology
WOS SubjectChemistry, Analytical ; Food Science & Technology
WOS IDWOS:000467667900008
PublisherAOAC INT, 481 N FREDRICK AVE, STE 500, GAITHERSBURG, MD 20877-2504 USA
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Document TypeJournal article
专题Institute of Chinese Medical Sciences
Corresponding AuthorYing Wang
Affiliation1.University of Macau, Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medicine, Macau, China
2.Nanyang Technological University, Nanyang Environment and Water Research Institute, Residues and Resource Reclamation Centre, Singapore
3.Bino Limited Beijing, Beijing, China
First Author AffilicationInstitute of Chinese Medical Sciences
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
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Wan-Xin Zhang,In-Cheng Chao,De-Jun Hu,et al. Comparison of Antioxidant Activity and Main Active Compounds Among Different Parts of Alpinia officinarum Hance Using High-Performance Thin Layer Chromatography-Bioautography[J]. JOURNAL OF AOAC INTERNATIONAL,2019,102(3):726-733.
APA Wan-Xin Zhang.,In-Cheng Chao.,De-Jun Hu.,Farid Shakerian.,Liya Ge.,...&Shao-Ping Li.(2019).Comparison of Antioxidant Activity and Main Active Compounds Among Different Parts of Alpinia officinarum Hance Using High-Performance Thin Layer Chromatography-Bioautography.JOURNAL OF AOAC INTERNATIONAL,102(3),726-733.
MLA Wan-Xin Zhang,et al."Comparison of Antioxidant Activity and Main Active Compounds Among Different Parts of Alpinia officinarum Hance Using High-Performance Thin Layer Chromatography-Bioautography".JOURNAL OF AOAC INTERNATIONAL 102.3(2019):726-733.
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