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Venom Peptides and Toxins - A Prospective Spearhead in Cancer Treatment
Wong, Janet P. C.; Li, Bin; Kwok, Hang F.
2017
Source PublicationCOMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
ISSN1386-2073
Volume20Issue:5Pages:357-375
Abstract

Background & Aim: Cancer is a condition of genetically or environmentally mutated, uncontrollable cell growth that directly affects human morbidity and mortality. Many treatments have been adopted to reduce cancer cell proliferation; however, new mutated developments of some cancer cells have started to show resistance towards current therapies and treatments that cause some drugs to lose their efficacy. Additionally, deleterious side-effects of some hard application methods like radiation therapy, chemotherapy, and surgery are less favorable. Accumulative research effort has revealed that peptides and toxins identified from underutilized natural sources including venomous reptiles, amphibians, insects, arachnids, marine organisms and plants are increasingly being employed in cancer treatment. This demands more peptides / toxins to be identified from underutilized natural sources as an alternative therapeutic approach.

KeywordCancer Venom Reptiles Amphibians Insects Plants Conjugated Peptide Toxin Mechanisms
DOIhttp://doi.org/10.2174/1386207320666170621130425
URLView the original
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry ; Pharmacology & Pharmacy
WOS SubjectBiochemical Research Methods ; Chemistry, Applied ; Pharmacology & Pharmacy
WOS IDWOS:000410625500002
PublisherBENTHAM SCIENCE PUBL LTD
The Source to ArticleWOS
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被引频次[WOS]:2   [WOS记录]     [WOS相关记录]
Document TypeJournal article
专题Faculty of Health Sciences
AffiliationFaculty of Health Sciences, University of Macau, Avenida da Universidade, Taipa, Macau SAR. China.
First Author AffilicationFaculty of Health Sciences
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Wong, Janet P. C.,Li, Bin,Kwok, Hang F.. Venom Peptides and Toxins - A Prospective Spearhead in Cancer Treatment[J]. COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING,2017,20(5):357-375.
APA Wong, Janet P. C.,Li, Bin,&Kwok, Hang F..(2017).Venom Peptides and Toxins - A Prospective Spearhead in Cancer Treatment.COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING,20(5),357-375.
MLA Wong, Janet P. C.,et al."Venom Peptides and Toxins - A Prospective Spearhead in Cancer Treatment".COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING 20.5(2017):357-375.
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