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Comorbid Moderate-Severe Depressive Symptoms and their Association with Quality of Life in Chinese Patients with Schizophrenia Treated in Primary Care
Hou, CL1; Ma, XR2; Cai, MY3; Li, Y4; Zang, Y5; Jia, FJ1; Lin, YQ1; Chiu, HFK6; Ungvari, GS7,8; Hall, BJ9; Zhong, BL6; Cao, XL5; Xiang, YT10
2016-11
Source PublicationCOMMUNITY MENTAL HEALTH JOURNAL
ISSN0010-3853
Volume52Issue:8Pages:921-926
Abstract

This study described the prevalence and correlates of comorbid moderate-severe depressive symptoms (comorbid depression thereafter) and theirassociation with quality of life (QOL) in schizophrenia patients treated in primary care. 623 schizophrenia patients were enrolled. Patients' socio-demographic and clinical characteristics including comorbid depression [defined as a total score of 18 or above on the Montgomery-Asberg Depression Rating Scale (MADRS)] were recorded. Depressive symptoms (defined as a total score of 9 or above on the MADRS) were present in 54.1 % of patients, while 17.7 % had comorbid depression. Analysis of covariance revealed that comorbid depression was significantly associated with lower mental QOL. Multiple logistic regression analysis revealed that more severe positive and negative symptoms, anxiety symptoms, use of first-generation antipsychotics and antidepressants, were independently associated with comorbid depression. Given the negative association between comorbid depression and QOL, attempts to address comorbid depression in schizophrenia patients treated in primary care should be made.

KeywordSchizophrenia Depressive Symptoms Community-dwelling Primary Care China
DOI10.1007/s10597-016-0023-5
Indexed BySSCI
Language英语
WOS Research AreaHealth Care Sciences & Services ; Public, Environmental & Occupational Health ; Psychiatry
WOS SubjectHealth Care Sciences & Services ; Public, Environmental & Occupational Health ; Psychiatry
WOS IDWOS:000388590000007
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Cited Times [WOS]:3   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Social Sciences
DEPARTMENT OF PSYCHOLOGY
Affiliation1.Guangdong Acad Med Sci, Guangdong Gen Hosp, Guangdong Mental Hlth Ctr, Guangzhou, Guangdong, Peoples R China
2.Ningxia Ning An Hosp, Ningxia Mental Hlth Ctr, Ningxia, Peoples R China
3.Guangzhou Yuexiu Ctr Dis Control & Prevent, Guangzhou, Guangdong, Peoples R China
4.Capital Med Univ, Beijing Anding Hosp, Mood Disorders Ctr, Beijing, Peoples R China
5.Shenzhen Mental Hlth Ctr, Shenzhen Kangning Hosp, Shenzhen Inst Mental Hlth, Shenzhen Key Lab Psychol Healthcare, Shenzhen, Peoples R China
6.Chinese Univ Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R China
7.Univ Western Australia, Sch Psychiat & Clin Neurosci, Perth, WA, Australia
8.Univ Notre Dame Australia, Marian Ctr, Perth, WA, Australia
9.Univ Macau, Dept Psychol, Macau, Peoples R China
10.Univ Macau, Unit Psychiat, Fac Hlth Sci, Ave Univ,3-F,Bldg E12, Macau, Peoples R China
Recommended Citation
GB/T 7714
Hou, CL,Ma, XR,Cai, MY,et al. Comorbid Moderate-Severe Depressive Symptoms and their Association with Quality of Life in Chinese Patients with Schizophrenia Treated in Primary Care[J]. COMMUNITY MENTAL HEALTH JOURNAL,2016,52(8):921-926.
APA Hou, CL.,Ma, XR.,Cai, MY.,Li, Y.,Zang, Y.,...&Xiang, YT.(2016).Comorbid Moderate-Severe Depressive Symptoms and their Association with Quality of Life in Chinese Patients with Schizophrenia Treated in Primary Care.COMMUNITY MENTAL HEALTH JOURNAL,52(8),921-926.
MLA Hou, CL,et al."Comorbid Moderate-Severe Depressive Symptoms and their Association with Quality of Life in Chinese Patients with Schizophrenia Treated in Primary Care".COMMUNITY MENTAL HEALTH JOURNAL 52.8(2016):921-926.
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