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The application of a G-quadruplex based assay with an iridium(III) complex to arsenic ion detection and its utilization in a microfluidic chip
Lin, Sheng1; Wang, Wanhe1; Hu, Chong1; Yang, Guanjun2; Ko, Chung-Nga1; Ren, Kangning1; Leung, Chung-Hang2; Ma, Dik-Lung1
2017-01-21
Source PublicationJOURNAL OF MATERIALS CHEMISTRY B
ISSN2050-750X
Volume5Issue:3Pages:479-484
Abstract

In this work, the iridium(III) complex 1 was synthesized and employed in constructing an assay which is based on a G-quadruplex for detecting arsenic ions in aqueous solution. The assay achieved a detection limit of 7.6 nM (ca. 0.57 mu g L-1) and showed high selectivity towards arsenic ions over other metal ions. Additionally, the assay could function in natural water and a simple microfluidic chip was used to investigate the potential of this platform for real-time detection.

DOI10.1039/c6tb02656g
URLView the original
Indexed BySCI
Language英语
WOS Research AreaMaterials Science
WOS SubjectMaterials Science, bioMaterials
WOS IDWOS:000394431600010
PublisherROYAL SOC CHEMISTRY
The Source to ArticleWOS
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Cited Times [WOS]:33   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorRen, Kangning; Leung, Chung-Hang; Ma, Dik-Lung
Affiliation1.Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, China
2.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Lin, Sheng,Wang, Wanhe,Hu, Chong,et al. The application of a G-quadruplex based assay with an iridium(III) complex to arsenic ion detection and its utilization in a microfluidic chip[J]. JOURNAL OF MATERIALS CHEMISTRY B,2017,5(3):479-484.
APA Lin, Sheng.,Wang, Wanhe.,Hu, Chong.,Yang, Guanjun.,Ko, Chung-Nga.,...&Ma, Dik-Lung.(2017).The application of a G-quadruplex based assay with an iridium(III) complex to arsenic ion detection and its utilization in a microfluidic chip.JOURNAL OF MATERIALS CHEMISTRY B,5(3),479-484.
MLA Lin, Sheng,et al."The application of a G-quadruplex based assay with an iridium(III) complex to arsenic ion detection and its utilization in a microfluidic chip".JOURNAL OF MATERIALS CHEMISTRY B 5.3(2017):479-484.
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