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A rhodium(III)-based inhibitor of autotaxin with antiproliferative activity
Kang, Tian-Shu1; Wang, Wanhe2; Zhong, Hai-Jing1; Liang, Jia-Xin1; Ko, Chung-Nga2; Lu, Jin-Jian1; Chen, Xiu-Ping1; Ma, Dik-Lung2; Leung, Chung-Hang1
2017-02
Source PublicationBIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
ISSN0304-4165
Volume1861Issue:2Pages:256-263
Abstract

Background: Cancer of the skin is by far the most common of all cancers. Melanoma accounts for only about 1% of skin cancers but causes a large majority of skin cancer deaths. Autotaxin (ATX), also known as ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2), regulates physiological and pathological functions of lysophosphatidic acid (LPA), and is thus an important therapeutic target.

KeywordRhodium Complex Anticancer Melanoma Autotaxin Inhibitor
DOI10.1016/j.bbagen.2016.11.032
URLView the original
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Biophysics
WOS SubjectBiochemistry & Molecular Biology ; Biophysics
WOS IDWOS:000392680200024
PublisherELSEVIER SCIENCE BV
The Source to ArticleWOS
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Cited Times [WOS]:8   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Co-First AuthorKang, Tian-Shu
Corresponding AuthorMa, Dik-Lung; Leung, Chung-Hang
Affiliation1.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, Macao, China
2.Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
First Author AffilicationInstitute of Chinese Medical Sciences
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Kang, Tian-Shu,Wang, Wanhe,Zhong, Hai-Jing,et al. A rhodium(III)-based inhibitor of autotaxin with antiproliferative activity[J]. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,2017,1861(2):256-263.
APA Kang, Tian-Shu.,Wang, Wanhe.,Zhong, Hai-Jing.,Liang, Jia-Xin.,Ko, Chung-Nga.,...&Leung, Chung-Hang.(2017).A rhodium(III)-based inhibitor of autotaxin with antiproliferative activity.BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,1861(2),256-263.
MLA Kang, Tian-Shu,et al."A rhodium(III)-based inhibitor of autotaxin with antiproliferative activity".BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1861.2(2017):256-263.
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