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Comorbid Moderate–Severe Depressive Symptoms and their Association with Quality of Life in Chinese Patients with Schizophrenia Treated in Primary Care
Hou,Cai Lan1; Ma,Xin Rong2; Cai,Mei Ying3; Li,Yan4; Zang,Yu5; Jia,Fu Jun1; Lin,Yong Qiang1; Chiu,Helen F.K.6; Ungvari,Gabor S.7,8; Hall,Brian J.9; Zhong,Bao Liang6; Cao,Xiao Lan5; Xiang,Yu Tao10
2019-06-19
Source PublicationCommunity Mental Health Journal
ISSN15732789 00103853
Volume52Issue:8Pages:921-926
AbstractThis study described the prevalence and correlates of comorbid moderate–severe depressive symptoms (comorbid depression thereafter) and their association with quality of life (QOL) in schizophrenia patients treated in primary care. 623 schizophrenia patients were enrolled. Patients’ socio-demographic and clinical characteristics including comorbid depression [defined as a total score of 18 or above on the Montgomery–Asberg Depression Rating Scale (MADRS)] were recorded. Depressive symptoms (defined as a total score of 9 or above on the MADRS) were present in 54.1 % of patients, while 17.7 % had comorbid depression. Analysis of covariance revealed that comorbid depression was significantly associated with lower mental QOL. Multiple logistic regression analysis revealed that more severe positive and negative symptoms, anxiety symptoms, use of first-generation antipsychotics and antidepressants, were independently associated with comorbid depression. Given the negative association between comorbid depression and QOL, attempts to address comorbid depression in schizophrenia patients treated in primary care should be made.
KeywordChina Community-dwelling Depressive symptoms Primary care Schizophrenia
DOI10.1007/s10597-016-0023-5
URLView the original
Language英语
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Cited Times [WOS]:3   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Affiliation1.Guangdong Mental Health CenterGuangdong General HospitalGuangdong Academy of Medical Sciences,Guangzhou,China
2.Ningxia Mental Health CenterNingxia Ning-An Hospital,Yinchuan,China
3.Guangzhou Yuexiu Center for Disease Control and Prevention,Guangzhou,China
4.Mood Disorders CentreBeijing Anding HospitalCapital Medical University,Beijing,China
5.Shenzhen Key Laboratory for Psychological HealthcareShenzhen Institute of Mental HealthShenzhen Kangning HospitalShenzhen Mental Health Center,Shenzhen,China
6.Department of PsychiatryChinese University of Hong Kong,Hong Kong
7.School of Psychiatry and Clinical NeurosciencesUniversity of Western Australia,Perth,Australia
8.Marian CentreThe University of Notre Dame Australia,Perth,Australia
9.Department of PsychologyUniversity of Macau,Macao SAR,Macao
10.Unit of PsychiatryFaculty of Health SciencesUniversity of Macau,Macau SAR,Macao
Recommended Citation
GB/T 7714
Hou,Cai Lan,Ma,Xin Rong,Cai,Mei Ying,et al. Comorbid Moderate–Severe Depressive Symptoms and their Association with Quality of Life in Chinese Patients with Schizophrenia Treated in Primary Care[J]. Community Mental Health Journal,2019,52(8):921-926.
APA Hou,Cai Lan.,Ma,Xin Rong.,Cai,Mei Ying.,Li,Yan.,Zang,Yu.,...&Xiang,Yu Tao.(2019).Comorbid Moderate–Severe Depressive Symptoms and their Association with Quality of Life in Chinese Patients with Schizophrenia Treated in Primary Care.Community Mental Health Journal,52(8),921-926.
MLA Hou,Cai Lan,et al."Comorbid Moderate–Severe Depressive Symptoms and their Association with Quality of Life in Chinese Patients with Schizophrenia Treated in Primary Care".Community Mental Health Journal 52.8(2019):921-926.
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