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Prevalence of Major Depression and Its Associations With Demographic and Clinical Characteristics and Quality of Life in Chinese Patients With HBV-related Liver Diseases
Liu,Mei1; Li,Lu2; Zheng,Su Jun1; Zhao,Jing1; Ungvari,Gabor S.3,4; Hall,Brian J.5,6; Duan,Zhong Ping1; Xiang,Yu Tao2
2019-06-19
Source PublicationArchives of Psychiatric Nursing
ISSN08839417
Volume31Issue:3Pages:287-290
AbstractBACKGROUND There are no data about the frequency of major depression in patients with liver disease related to Hepatitis B virus (HBV) in China. This study examined the prevalence of major depression and its clinical correlates and association with quality of life (QOL) in patients with HBV-related liver diseases. METHOD Altogether 634 patients with HBV-related liver diseases met study entry criteria and completed the survey. The diagnosis of major depression was established with the Mini International Neuropsychiatric Interview (MINI). Socio-demographic and clinical characteristics, Global Assessment of Functioning (GAF) and QOL were measured. RESULTS The prevalence of major depression was 6.4%. Multivariable logistic regression analyses revealed that insomnia (P = 0.01, OR = 5.5, 95%CI = 1.4–21.6) and global functioning (P < 0.001, OR = 0.6, 95% CI = 0.5–0.7) were independently associated with major depression. Major depression was associated with both poor physical (F  = 4.0, P = 0.04) and mental QOL (F  = 26.2, P < 0.001). CONCLUSIONS Given the negative impact of depression on patients’ QOL, more attempts should be made to identify and treat it in HBV-related diseases.
KeywordChina Depression HBV-related liver diseases Quality of life
DOI10.1016/j.apnu.2017.02.004
URLView the original
Language英语
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Document TypeJournal article
CollectionUniversity of Macau
Affiliation1.Artificial Liver CenterBeijing YouAn HospitalCapital Medical University,Beijing,China
2.Unit of PsychiatryFaculty of Health SciencesUniversity of Macau,Macao
3.The University of Notre Dame Australia/Marian Centre,Perth,Australia
4.School of Psychiatry & Clinical NeurosciencesUniversity of Western Australia,Perth,Australia
5.Global and Community Mental Health Research GroupDepartment of PsychologyUniversity of Macau,Macao
6.Department of HealthBehavior and SocietyJohns Hopkins Bloomberg School of Public Health,Baltimore,United States
Recommended Citation
GB/T 7714
Liu,Mei,Li,Lu,Zheng,Su Jun,et al. Prevalence of Major Depression and Its Associations With Demographic and Clinical Characteristics and Quality of Life in Chinese Patients With HBV-related Liver Diseases[J]. Archives of Psychiatric Nursing,2019,31(3):287-290.
APA Liu,Mei.,Li,Lu.,Zheng,Su Jun.,Zhao,Jing.,Ungvari,Gabor S..,...&Xiang,Yu Tao.(2019).Prevalence of Major Depression and Its Associations With Demographic and Clinical Characteristics and Quality of Life in Chinese Patients With HBV-related Liver Diseases.Archives of Psychiatric Nursing,31(3),287-290.
MLA Liu,Mei,et al."Prevalence of Major Depression and Its Associations With Demographic and Clinical Characteristics and Quality of Life in Chinese Patients With HBV-related Liver Diseases".Archives of Psychiatric Nursing 31.3(2019):287-290.
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