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Harmonic generation microscopy of bone microenvironment in vivo
Wu, Pei-Chun1,2; Shen, Yu-Fang3; Sun, Chi-Kuang4,5; Lin, Charles P.6; Liu, Tzu-Ming1,2
2018-09
Source PublicationOPTICS COMMUNICATIONS
ISSN0030-4018
Volume422Pages:52-55
Abstract

Here we report and review the investigation of bone microenvironment in vivo with harmonic generation microscopy. Excited by an infrared femtosecond laser, the second harmonic generation images can reveal the bone structures and boundaries. The third harmonic generation images can reveal the osteocytes, connecting canaliculi, and granular bone marrow cells. These imaging features can be used to observe and analyze the histology of the bone microenvironment in the future. (C) 2018 Elsevier B.V. All rights reserved.

KeywordOsteocyte Bone Marrow Cr:Forsterite Femtosecond Third Harmonic Generation
DOIhttp://doi.org/10.1016/j.optcom.2018.01.023
URLView the original
Indexed BySCI
Language英语
WOS Research AreaOptics
WOS SubjectOptics
WOS IDWOS:000436512800008
PublisherELSEVIER SCIENCE BV
The Source to ArticleWOS
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Cited Times [WOS]:1   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Corresponding AuthorLiu, Tzu-Ming
Affiliation1.Faculty of Health Sciences, University of Macau, Macao
2.Molecular Imaging Center, National Taiwan University, Taipei 10617, Taiwan
3.Department of Bioinformatics and Medical Engineering, Asia University, Taichung 41354, Taiwan
4.Graduate Institute of Photonics and Optoelectronics, National Taiwan University, Taipei 10617, Taiwan
5.Department of Electrical Engineering, National Taiwan University, Taipei 10617, Taiwan
6.Wellman Center for Photomedicine and Center for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA
First Author AffilicationFaculty of Health Sciences
Corresponding Author AffilicationFaculty of Health Sciences
Recommended Citation
GB/T 7714
Wu, Pei-Chun,Shen, Yu-Fang,Sun, Chi-Kuang,et al. Harmonic generation microscopy of bone microenvironment in vivo[J]. OPTICS COMMUNICATIONS,2018,422:52-55.
APA Wu, Pei-Chun,Shen, Yu-Fang,Sun, Chi-Kuang,Lin, Charles P.,&Liu, Tzu-Ming.(2018).Harmonic generation microscopy of bone microenvironment in vivo.OPTICS COMMUNICATIONS,422,52-55.
MLA Wu, Pei-Chun,et al."Harmonic generation microscopy of bone microenvironment in vivo".OPTICS COMMUNICATIONS 422(2018):52-55.
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