UM
Neo-clerodane diterpenes and phytoecdysteroids from Ajuga decumbens Thunb. and evaluation of their effects on cytotoxic, superoxide anion generation and elastase release in vitro
Chen, Hao; Tang, Ben-Qin; Chen, Li; Liang, Jing-Yu; Sun, Jian-Bo
2018-09
Source PublicationFITOTERAPIA
ISSN0367-326X
Volume129Pages:7-12
AbstractFive novel compounds, including four neoclerodane diterpenoids, named ajugacumbins K-N (1-4) along with a phytoecdysterone, named ajugacetalsterone E (5), were isolated from the whole herbs of Ajuga decumbens (Labiatae). Their structures were elucidated on the basis of detailed spectroscopic analysis including IR, HRESIMS, CD, 1D and 2D NMR spectroscopic experiments. Compounds 1-5 were evaluated for their cytotoxic activities and the effects on superoxide anion generation and elastase release in FMLP/CB-induced human neutrophils.
KeywordAjuga decumbens Neoclerodane diterpenoids Phytoecdysterone Cytotoxic activities Superoxide anion generation Elastase release
DOI10.1016/j.fitote.2018.06.004
URLView the original
Indexed BySCI
Language英语
WOS Research AreaPharmacology & Pharmacy
WOS SubjectChemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000443663800002
PublisherELSEVIER SCIENCE BV
The Source to ArticleWOS
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Citation statistics
Cited Times [WOS]:2   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Recommended Citation
GB/T 7714
Chen, Hao,Tang, Ben-Qin,Chen, Li,et al. Neo-clerodane diterpenes and phytoecdysteroids from Ajuga decumbens Thunb. and evaluation of their effects on cytotoxic, superoxide anion generation and elastase release in vitro[J]. FITOTERAPIA,2018,129:7-12.
APA Chen, Hao,Tang, Ben-Qin,Chen, Li,Liang, Jing-Yu,&Sun, Jian-Bo.(2018).Neo-clerodane diterpenes and phytoecdysteroids from Ajuga decumbens Thunb. and evaluation of their effects on cytotoxic, superoxide anion generation and elastase release in vitro.FITOTERAPIA,129,7-12.
MLA Chen, Hao,et al."Neo-clerodane diterpenes and phytoecdysteroids from Ajuga decumbens Thunb. and evaluation of their effects on cytotoxic, superoxide anion generation and elastase release in vitro".FITOTERAPIA 129(2018):7-12.
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