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A MnO2 nanosheet-assisted GSH detection platform using an iridium(III) complex as a switch-on luminescent probe
Dong, Zhen-Zhen1; Lu, Lihua1,2; Ko, Chung-Nga1; Yang, Chao3; Li, Shengnan3; Lee, Ming-Yuen3; Leung, Chung-Hang3; Ma, Dik-Lung1
2017-04-14
Source PublicationNANOSCALE
ISSN2040-3364
Volume9Issue:14Pages:4677-4682
Abstract

A rapid and sensitive detection platform for GSH has been constructed by combining a MnO2 nanosheet with a luminescent iridium(III) complex [Ir(Cl-phq)2(Cl-phen)]+. The MnO2 nanosheet was prepared by using a facile one-step approach and was characterized by TEM. The luminescence intensity of the detection platform responded linearly with the GSH concentration from 1 to 200 mu M (R-2 = 0.9951), and the detection limit for GSH was 0.13 mu M. More importantly, practical application of the detection platform for visualizing the intracellular GSH distribution in living zebrafish has also been demonstrated.

DOI10.1039/c6nr08357a
URLView the original
Indexed BySCI
Language英语
WOS Research AreaChemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS SubjectChemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied
WOS IDWOS:000398954800006
PublisherROYAL SOC CHEMISTRY
The Source to ArticleWOS
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Cited Times [WOS]:39   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorLeung, Chung-Hang; Ma, Dik-Lung
Affiliation1.Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, China
2.College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao 266109, China
3.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Dong, Zhen-Zhen,Lu, Lihua,Ko, Chung-Nga,et al. A MnO2 nanosheet-assisted GSH detection platform using an iridium(III) complex as a switch-on luminescent probe[J]. NANOSCALE,2017,9(14):4677-4682.
APA Dong, Zhen-Zhen.,Lu, Lihua.,Ko, Chung-Nga.,Yang, Chao.,Li, Shengnan.,...&Ma, Dik-Lung.(2017).A MnO2 nanosheet-assisted GSH detection platform using an iridium(III) complex as a switch-on luminescent probe.NANOSCALE,9(14),4677-4682.
MLA Dong, Zhen-Zhen,et al."A MnO2 nanosheet-assisted GSH detection platform using an iridium(III) complex as a switch-on luminescent probe".NANOSCALE 9.14(2017):4677-4682.
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