UM  > 健康科學學院
Inhibiting Glycogen Synthase Kinase 3 Reverses Obesity-Induced White Adipose Tissue Inflammation by Regulating Apoptosis Inhibitor of Macrophage/CD5L-Mediated Macrophage Migration
Wang, Li1; Wang, Yuan1; Zhang, Chao1; Li, Jingjing1; Meng, Yuan1; Dou, Man1; Noguchi, Constance Tom2; Di, Lijun1
2018-09
Source PublicationARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
ISSN1079-5642
Volume38Issue:9Pages:2103-2116
Abstract

Objective Obesity-induced inflammation in white adipose tissue, characterized by increased macrophage infiltration and associated with macrophage population shift from anti-inflammatory M2 to proinflammatory M1 macrophages, largely contributes to obesity-induced insulin resistance and influences type 2 diabetes mellitus pathogenesis. GSK3 (glycogen synthase kinase 3), a serine/threonine kinase, has been reported to participate in various cellular processes. We sought to examine the potential mechanism by which GSK3, a serine/threonine kinase implicated in various cellular processes, modulates obesity-induced visceral adipose tissue (VAT) inflammation.

KeywordAdipose Tissue Gsk3 Inflammation Macrophages Obesity
DOI10.1161/ATVBAHA.118.311363
URLView the original
Indexed BySCI
Language英语
WOS Research AreaHematology ; Cardiovascular System & Cardiology
WOS SubjectHematology ; Peripheral Vascular Disease
WOS IDWOS:000442507900015
PublisherLIPPINCOTT WILLIAMS & WILKINS
The Source to ArticleWOS
Fulltext Access
Citation statistics
Cited Times [WOS]:2   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Affiliation1.Faculty of Health Sciences, University of Macau, Macau SAR, China
2.Molecular Medicine Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD (T.N.).
First Author AffilicationFaculty of Health Sciences
Recommended Citation
GB/T 7714
Wang, Li,Wang, Yuan,Zhang, Chao,et al. Inhibiting Glycogen Synthase Kinase 3 Reverses Obesity-Induced White Adipose Tissue Inflammation by Regulating Apoptosis Inhibitor of Macrophage/CD5L-Mediated Macrophage Migration[J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY,2018,38(9):2103-2116.
APA Wang, Li.,Wang, Yuan.,Zhang, Chao.,Li, Jingjing.,Meng, Yuan.,...&Di, Lijun.(2018).Inhibiting Glycogen Synthase Kinase 3 Reverses Obesity-Induced White Adipose Tissue Inflammation by Regulating Apoptosis Inhibitor of Macrophage/CD5L-Mediated Macrophage Migration.ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY,38(9),2103-2116.
MLA Wang, Li,et al."Inhibiting Glycogen Synthase Kinase 3 Reverses Obesity-Induced White Adipose Tissue Inflammation by Regulating Apoptosis Inhibitor of Macrophage/CD5L-Mediated Macrophage Migration".ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 38.9(2018):2103-2116.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Wang, Li]'s Articles
[Wang, Yuan]'s Articles
[Zhang, Chao]'s Articles
Baidu academic
Similar articles in Baidu academic
[Wang, Li]'s Articles
[Wang, Yuan]'s Articles
[Zhang, Chao]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Wang, Li]'s Articles
[Wang, Yuan]'s Articles
[Zhang, Chao]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.