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An eco-friendly in situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine
Li, Shengke1; Jiang, Nan2; Zhao, Wenxuan1; Ding, Yuan-Fu1,3; Zheng, Ying1; Wang, Lian-Hui3; Zheng, Jun2; Wang, Ruibing1
2017-05-28
Source PublicationCHEMICAL COMMUNICATIONS
ISSN1359-7345
Volume53Issue:43Pages:5870-5873
Other Abstract

We report an unprecedented, eco-friendly, in situ activatable model antibiotic, phenylalanyl-polyethylenimine (PhePEI), to potentially diminish antibiotic pollution of the environment and associated antibiotic resistance. The inactive PhePEI can be reversibly activated upon supramolecular crosslinking by cucurbit[8]uril, conferring potent antibacterial activity.

DOIhttp://doi.org/10.1039/c7cc02466e
URLView the original
Indexed BySCI
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000402296200019
PublisherROYAL SOC CHEMISTRY
The Source to ArticleWOS
Fulltext Access
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Cited Times [WOS]:26   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Co-First AuthorLi, Shengke
Corresponding AuthorZheng, Jun; Wang, Ruibing
Affiliation1.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Avenida da Universidade, Taipa, Macau SAR, China
2.Faculty of Health Sciences, University of Macau, Avenida da Universidade, Taipa, Macau SAR, China
3.Key Laboratory for Organic Electronics and Information Displays, Institute of Advanced Materials, Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210046, China
First Author AffilicationInstitute of Chinese Medical Sciences
Corresponding Author AffilicationFaculty of Health Sciences;  Institute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Li, Shengke,Jiang, Nan,Zhao, Wenxuan,et al. An eco-friendly in situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine[J]. CHEMICAL COMMUNICATIONS,2017,53(43):5870-5873.
APA Li, Shengke.,Jiang, Nan.,Zhao, Wenxuan.,Ding, Yuan-Fu.,Zheng, Ying.,...&Wang, Ruibing.(2017).An eco-friendly in situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine.CHEMICAL COMMUNICATIONS,53(43),5870-5873.
MLA Li, Shengke,et al."An eco-friendly in situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine".CHEMICAL COMMUNICATIONS 53.43(2017):5870-5873.
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