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Annona species (Annonaceae): a rich source of potential antitumor agents?
Tundis, Rosa1; Xiao, Jianbo2,3; Loizzo, Monica R.1
2017-06
Source PublicationANNALS OF THE NEW YORK ACADEMY OF SCIENCES
ISSN0077-8923
Volume1398Issue:1Pages:30-36
Abstract

Plants have provided the basis of traditional medicine systems throughout the world for thousands of years and continue to yield molecules for new remedies. We analyzed studies published from 2009 to 2016 on the Annona species (Annonaceae), including A. coriacea, A. crassifolia, A. hypoglauca, A. muricata, A. squamosa, A. sylvatica, and A. vepretorum, as sources of potential antitumor agents. Here, we report and discuss the mechanisms of action and structure-activity relationships of the most active Annona constituents. Annonaceous acetogenins are one of the most promising classes of natural products, owing to their potential antitumor activity. However, their neurotoxicity should not be underestimated.

KeywordAnnona Tumor Mechanisms Natural Compounds
DOI10.1111/nyas.13339
URLView the original
Indexed BySCI
Language英语
WOS Research AreaScience & Technology - Other Topics
WOS SubjectMultidisciplinary Sciences
WOS IDWOS:000405457600003
PublisherWILEY
The Source to ArticleWOS
Fulltext Access
Citation statistics
Cited Times [WOS]:9   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Cosenza, Italy
2.Institute of ChineseMedical Sciences, State Key Laboratory of Quality Research in Chinese Medicine, Macau University, Taipa, Macau
3.Collegeof Food Science, Fujian Agriculture and Forest University, Fuzhou, P.R. China
Recommended Citation
GB/T 7714
Tundis, Rosa,Xiao, Jianbo,Loizzo, Monica R.. Annona species (Annonaceae): a rich source of potential antitumor agents?[J]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES,2017,1398(1):30-36.
APA Tundis, Rosa,Xiao, Jianbo,&Loizzo, Monica R..(2017).Annona species (Annonaceae): a rich source of potential antitumor agents?.ANNALS OF THE NEW YORK ACADEMY OF SCIENCES,1398(1),30-36.
MLA Tundis, Rosa,et al."Annona species (Annonaceae): a rich source of potential antitumor agents?".ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 1398.1(2017):30-36.
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